Disparities in obstetric hemorrhage outcomes

Abstract Both the maternal and fetal outcomes of pregnancy vary greatly according to a pregnant woman’s community and her condition. The most devastating outcome is the death of a mother. In 2017, there were ≈295,000 maternal deaths globally with dramatic differences in maternal mortality based on g...

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Main Authors: Andra H. James, Jerome J. Federspiel, Homa K. Ahmadzia
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:Research and Practice in Thrombosis and Haemostasis
Subjects:
Online Access:https://doi.org/10.1002/rth2.12656
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author Andra H. James
Jerome J. Federspiel
Homa K. Ahmadzia
author_facet Andra H. James
Jerome J. Federspiel
Homa K. Ahmadzia
author_sort Andra H. James
collection DOAJ
description Abstract Both the maternal and fetal outcomes of pregnancy vary greatly according to a pregnant woman’s community and her condition. The most devastating outcome is the death of a mother. In 2017, there were ≈295,000 maternal deaths globally with dramatic differences in maternal mortality based on geographic region, country, and women’s underlying conditions. Worldwide, the leading cause of maternal death is hemorrhage, comprising 94% of maternal deaths, with most cases occurring in low‐ or middle‐income countries. Whether a hemorrhage originates from inside the uterus (80%‐90%), from lacerations or incisions (10%‐20%), or from an underlying coagulopathy (<1%), an acute acquired coagulopathy will evolve unless the hemorrhage is controlled. In low‐ or middle‐income countries, the full range of resources to control hemorrhage is not available, but besides the usual obstetric measures, blood availability, hemostatic medication, and hematologic expertise are necessary to save mothers’ lives. Hemostasis and thrombosis experts can address the disparities in obstetric hemorrhage outcomes not only as providers but as consultants, researchers, and advocates.
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spelling doaj.art-4b2bebf8b4e440368993ba71f198c3e52023-09-03T08:07:21ZengElsevierResearch and Practice in Thrombosis and Haemostasis2475-03792022-01-0161n/an/a10.1002/rth2.12656Disparities in obstetric hemorrhage outcomesAndra H. James0Jerome J. Federspiel1Homa K. Ahmadzia2Department of Obstetrics and Gynecology Division of Maternal‐Fetal Medicine Duke University Durham North Carolina USADepartment of Obstetrics and Gynecology Division of Maternal‐Fetal Medicine Duke University Durham North Carolina USADepartment of Obstetrics and Gynecology Division of Maternal‐Fetal Medicine The George Washington University Washington District of Columbia USAAbstract Both the maternal and fetal outcomes of pregnancy vary greatly according to a pregnant woman’s community and her condition. The most devastating outcome is the death of a mother. In 2017, there were ≈295,000 maternal deaths globally with dramatic differences in maternal mortality based on geographic region, country, and women’s underlying conditions. Worldwide, the leading cause of maternal death is hemorrhage, comprising 94% of maternal deaths, with most cases occurring in low‐ or middle‐income countries. Whether a hemorrhage originates from inside the uterus (80%‐90%), from lacerations or incisions (10%‐20%), or from an underlying coagulopathy (<1%), an acute acquired coagulopathy will evolve unless the hemorrhage is controlled. In low‐ or middle‐income countries, the full range of resources to control hemorrhage is not available, but besides the usual obstetric measures, blood availability, hemostatic medication, and hematologic expertise are necessary to save mothers’ lives. Hemostasis and thrombosis experts can address the disparities in obstetric hemorrhage outcomes not only as providers but as consultants, researchers, and advocates.https://doi.org/10.1002/rth2.12656blood availabilitycoagulopathyhemorrhagematernal mortalitypregnancy
spellingShingle Andra H. James
Jerome J. Federspiel
Homa K. Ahmadzia
Disparities in obstetric hemorrhage outcomes
Research and Practice in Thrombosis and Haemostasis
blood availability
coagulopathy
hemorrhage
maternal mortality
pregnancy
title Disparities in obstetric hemorrhage outcomes
title_full Disparities in obstetric hemorrhage outcomes
title_fullStr Disparities in obstetric hemorrhage outcomes
title_full_unstemmed Disparities in obstetric hemorrhage outcomes
title_short Disparities in obstetric hemorrhage outcomes
title_sort disparities in obstetric hemorrhage outcomes
topic blood availability
coagulopathy
hemorrhage
maternal mortality
pregnancy
url https://doi.org/10.1002/rth2.12656
work_keys_str_mv AT andrahjames disparitiesinobstetrichemorrhageoutcomes
AT jeromejfederspiel disparitiesinobstetrichemorrhageoutcomes
AT homakahmadzia disparitiesinobstetrichemorrhageoutcomes