Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients
Background and Aims. Tympanosclerosis (TS) is a scarring process that may occur during otitis media. Aortic stiffness (AS) is a significant predictor for the development of heart diseases due to its close relationship with atherosclerosis. Similar pathophysiological processes based on inflammation m...
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| Format: | Article |
| Language: | English |
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Palacký University Olomouc, Faculty of Medicine and Dentistry
2023-12-01
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| Series: | Biomedical Papers |
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| Online Access: | https://biomed.papers.upol.cz/artkey/bio-202304-0006_evaluation-of-aortic-stiffness-by-echocardiography-in-tympanosclerosis-patients.php |
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| author | Hikmet Hamur Oruc Alper Onk Resit Coskun Muharrem Said Cosgun Ismail Salcan Izzet Emir |
| author_facet | Hikmet Hamur Oruc Alper Onk Resit Coskun Muharrem Said Cosgun Ismail Salcan Izzet Emir |
| author_sort | Hikmet Hamur |
| collection | DOAJ |
| description | Background and Aims. Tympanosclerosis (TS) is a scarring process that may occur during otitis media. Aortic stiffness (AS) is a significant predictor for the development of heart diseases due to its close relationship with atherosclerosis. Similar pathophysiological processes based on inflammation may explain both TS and AS formation. This study aimed to determine echocardiographically whether aortic elasticity is impaired in TS-detected patients and to correlate blood inflammatory parameters with TS and aortic elasticity. Methods. Ninety-eight participants diagnosed with chronic otitis media were enrolled in the study. TS-detected 42 participants were assigned to the study group, while 56 without TS constituted the control group. The two groups' demographic, clinical, echocardiographic, and laboratory characteristics were comparable. Results. Demographic, clinical, and laboratory parameter differences were insignificant. Hs-CRP, neutrophil-to-lymphocyte ratio, and systemic immune-inflammation index were significantly higher in the study group than in the control group (P=0.018, P=0.003, P=0.019, respectively). The study group had significantly lower aortic strain (11.80 ± 4.84 vs. 16.30 ± 3.91; P<0.001) and distensibility (5.23 ± 2.68 vs. 7.24 ± 2.89; P=0.001) values than the control group. The AS index was significantly higher in the study group than in the control group (4.81 ± 2.41 vs. 3.12 ± 1.02; P<0.001). Conclusion. In TS-detected patients, AS parameters were found to be impaired. Aortic elasticity parameters measured by echocardiography, a non-invasive and easily accessible method, may signify early cardiovascular involvement in TS-developed patients. |
| first_indexed | 2024-03-09T01:03:38Z |
| format | Article |
| id | doaj.art-4b2c3d78fbbb4d37b39a95ab3ca34413 |
| institution | Directory Open Access Journal |
| issn | 1213-8118 1804-7521 |
| language | English |
| last_indexed | 2024-03-09T01:03:38Z |
| publishDate | 2023-12-01 |
| publisher | Palacký University Olomouc, Faculty of Medicine and Dentistry |
| record_format | Article |
| series | Biomedical Papers |
| spelling | doaj.art-4b2c3d78fbbb4d37b39a95ab3ca344132023-12-11T12:59:47ZengPalacký University Olomouc, Faculty of Medicine and DentistryBiomedical Papers1213-81181804-75212023-12-01167434735110.5507/bp.2022.031bio-202304-0006Evaluation of aortic stiffness by echocardiography in tympanosclerosis patientsHikmet Hamur0Oruc Alper Onk1Resit Coskun2Muharrem Said Cosgun3Ismail Salcan4Izzet Emir5Department of Cardiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, TurkeyDepartment of Cardiovascular Surgery, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan,TurkeyDepartment of Cardiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, TurkeyDepartment of Cardiology, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan, TurkeyDepartment of Otorhinolaryngology, Faculty of Medicine , Erzincan Binali Yildirim University, Erzincan, TurkeyDepartment of Cardiovascular Surgery, Faculty of Medicine, Erzincan Binali Yildirim University, Erzincan,TurkeyBackground and Aims. Tympanosclerosis (TS) is a scarring process that may occur during otitis media. Aortic stiffness (AS) is a significant predictor for the development of heart diseases due to its close relationship with atherosclerosis. Similar pathophysiological processes based on inflammation may explain both TS and AS formation. This study aimed to determine echocardiographically whether aortic elasticity is impaired in TS-detected patients and to correlate blood inflammatory parameters with TS and aortic elasticity. Methods. Ninety-eight participants diagnosed with chronic otitis media were enrolled in the study. TS-detected 42 participants were assigned to the study group, while 56 without TS constituted the control group. The two groups' demographic, clinical, echocardiographic, and laboratory characteristics were comparable. Results. Demographic, clinical, and laboratory parameter differences were insignificant. Hs-CRP, neutrophil-to-lymphocyte ratio, and systemic immune-inflammation index were significantly higher in the study group than in the control group (P=0.018, P=0.003, P=0.019, respectively). The study group had significantly lower aortic strain (11.80 ± 4.84 vs. 16.30 ± 3.91; P<0.001) and distensibility (5.23 ± 2.68 vs. 7.24 ± 2.89; P=0.001) values than the control group. The AS index was significantly higher in the study group than in the control group (4.81 ± 2.41 vs. 3.12 ± 1.02; P<0.001). Conclusion. In TS-detected patients, AS parameters were found to be impaired. Aortic elasticity parameters measured by echocardiography, a non-invasive and easily accessible method, may signify early cardiovascular involvement in TS-developed patients.https://biomed.papers.upol.cz/artkey/bio-202304-0006_evaluation-of-aortic-stiffness-by-echocardiography-in-tympanosclerosis-patients.phpaortic stiffnesstympanosclerosisinflammationechocardiography |
| spellingShingle | Hikmet Hamur Oruc Alper Onk Resit Coskun Muharrem Said Cosgun Ismail Salcan Izzet Emir Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients Biomedical Papers aortic stiffness tympanosclerosis inflammation echocardiography |
| title | Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients |
| title_full | Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients |
| title_fullStr | Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients |
| title_full_unstemmed | Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients |
| title_short | Evaluation of aortic stiffness by echocardiography in tympanosclerosis patients |
| title_sort | evaluation of aortic stiffness by echocardiography in tympanosclerosis patients |
| topic | aortic stiffness tympanosclerosis inflammation echocardiography |
| url | https://biomed.papers.upol.cz/artkey/bio-202304-0006_evaluation-of-aortic-stiffness-by-echocardiography-in-tympanosclerosis-patients.php |
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