Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities

Summary: Appropriate histone modifications emerge as essential cell fate regulators of neuronal identities across neocortical areas and layers. Here we showed that NSD1, the methyltransferase for di-methylated lysine 36 of histone H3 (H3K36me2), controls both area and layer identities of the neocort...

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Bibliographic Details
Main Authors: Yue Zheng, Chen Zhao, Qiulin Song, Lichao Xu, Bo Zhang, Guangda Hu, Xiangfei Kong, Shaowen Li, Xiang Li, Yin Shen, Lenan Zhuang, Min Wu, Ying Liu, Yan Zhou
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723015085