Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities

Histone methylation mediated by NSD1 is required for the establishment and maintenance of neuronal identities

Summary: Appropriate histone modifications emerge as essential cell fate regulators of neuronal identities across neocortical areas and layers. Here we showed that NSD1, the methyltransferase for di-methylated lysine 36 of histone H3 (H3K36me2), controls both area and layer identities of the neocort...

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Bibliographic Details
Main Authors: Yue Zheng, Chen Zhao, Qiulin Song, Lichao Xu, Bo Zhang, Guangda Hu, Xiangfei Kong, Shaowen Li, Xiang Li, Yin Shen, Lenan Zhuang, Min Wu, Ying Liu, Yan Zhou
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Cell Reports
Subjects:
CP: Neuroscience
CP: Molecular biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124723015085

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