Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”

Despite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today, particularly in high areas of unmet need such as cancer. We...

Full description

Bibliographic Details
Main Authors: Jan Lewis, Wendy Lipworth, Ian Kerridge
Format: Article
Language:English
Published: MDPI AG 2014-03-01
Series:Journal of Personalized Medicine
Subjects:
Online Access:http://www.mdpi.com/2075-4426/4/2/137
_version_ 1797935172912414720
author Jan Lewis
Wendy Lipworth
Ian Kerridge
author_facet Jan Lewis
Wendy Lipworth
Ian Kerridge
author_sort Jan Lewis
collection DOAJ
description Despite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today, particularly in high areas of unmet need such as cancer. We believe that this is because personalized medicine challenges the moral, economic and epistemological foundations of medicine. In this article, we briefly describe the scientific premises underpinning personalized medicine, contrast these with traditional paradigms of drug development, and then consider the ethical, economic and epistemological implications of this approach to medicine.
first_indexed 2024-04-10T18:10:16Z
format Article
id doaj.art-4b31d65e60ae4e64afcdb0b2faaf473f
institution Directory Open Access Journal
issn 2075-4426
language English
last_indexed 2024-04-10T18:10:16Z
publishDate 2014-03-01
publisher MDPI AG
record_format Article
series Journal of Personalized Medicine
spelling doaj.art-4b31d65e60ae4e64afcdb0b2faaf473f2023-02-02T11:01:31ZengMDPI AGJournal of Personalized Medicine2075-44262014-03-014213714610.3390/jpm4020137jpm4020137Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”Jan Lewis0Wendy Lipworth1Ian Kerridge2Centre for Values Ethics and Law in Medicine, University of Sydney Medical Foundation Building (K25), University of Sydney, Sydney, NSW 2006, AustraliaAustralian Institute of Health Innovation, University of New South Wales, Sydney, NSW 2052, AustraliaCentre for Values, Ethics and Law in Medicine, University of Sydney Medical Foundation Building (K25), University of Sydney, Sydney, NSW 2006, AustraliaDespite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today, particularly in high areas of unmet need such as cancer. We believe that this is because personalized medicine challenges the moral, economic and epistemological foundations of medicine. In this article, we briefly describe the scientific premises underpinning personalized medicine, contrast these with traditional paradigms of drug development, and then consider the ethical, economic and epistemological implications of this approach to medicine.http://www.mdpi.com/2075-4426/4/2/137individualized medicinepharmacologyethicseconomicsmedicineknowledge
spellingShingle Jan Lewis
Wendy Lipworth
Ian Kerridge
Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
Journal of Personalized Medicine
individualized medicine
pharmacology
ethics
economics
medicine
knowledge
title Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
title_full Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
title_fullStr Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
title_full_unstemmed Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
title_short Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
title_sort ethics evidence and economics in the pursuit of personalized medicine
topic individualized medicine
pharmacology
ethics
economics
medicine
knowledge
url http://www.mdpi.com/2075-4426/4/2/137
work_keys_str_mv AT janlewis ethicsevidenceandeconomicsinthepursuitofpersonalizedmedicine
AT wendylipworth ethicsevidenceandeconomicsinthepursuitofpersonalizedmedicine
AT iankerridge ethicsevidenceandeconomicsinthepursuitofpersonalizedmedicine