Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”
Despite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today, particularly in high areas of unmet need such as cancer. We...
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Format: | Article |
Language: | English |
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MDPI AG
2014-03-01
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Series: | Journal of Personalized Medicine |
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Online Access: | http://www.mdpi.com/2075-4426/4/2/137 |
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author | Jan Lewis Wendy Lipworth Ian Kerridge |
author_facet | Jan Lewis Wendy Lipworth Ian Kerridge |
author_sort | Jan Lewis |
collection | DOAJ |
description | Despite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today, particularly in high areas of unmet need such as cancer. We believe that this is because personalized medicine challenges the moral, economic and epistemological foundations of medicine. In this article, we briefly describe the scientific premises underpinning personalized medicine, contrast these with traditional paradigms of drug development, and then consider the ethical, economic and epistemological implications of this approach to medicine. |
first_indexed | 2024-04-10T18:10:16Z |
format | Article |
id | doaj.art-4b31d65e60ae4e64afcdb0b2faaf473f |
institution | Directory Open Access Journal |
issn | 2075-4426 |
language | English |
last_indexed | 2024-04-10T18:10:16Z |
publishDate | 2014-03-01 |
publisher | MDPI AG |
record_format | Article |
series | Journal of Personalized Medicine |
spelling | doaj.art-4b31d65e60ae4e64afcdb0b2faaf473f2023-02-02T11:01:31ZengMDPI AGJournal of Personalized Medicine2075-44262014-03-014213714610.3390/jpm4020137jpm4020137Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine”Jan Lewis0Wendy Lipworth1Ian Kerridge2Centre for Values Ethics and Law in Medicine, University of Sydney Medical Foundation Building (K25), University of Sydney, Sydney, NSW 2006, AustraliaAustralian Institute of Health Innovation, University of New South Wales, Sydney, NSW 2052, AustraliaCentre for Values, Ethics and Law in Medicine, University of Sydney Medical Foundation Building (K25), University of Sydney, Sydney, NSW 2006, AustraliaDespite enthusiastic advocacy for what personalized medicine might be able to deliver and major investments into the development of this, there remain disappointingly few examples of personalized medicine in routine clinical practice today, particularly in high areas of unmet need such as cancer. We believe that this is because personalized medicine challenges the moral, economic and epistemological foundations of medicine. In this article, we briefly describe the scientific premises underpinning personalized medicine, contrast these with traditional paradigms of drug development, and then consider the ethical, economic and epistemological implications of this approach to medicine.http://www.mdpi.com/2075-4426/4/2/137individualized medicinepharmacologyethicseconomicsmedicineknowledge |
spellingShingle | Jan Lewis Wendy Lipworth Ian Kerridge Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine” Journal of Personalized Medicine individualized medicine pharmacology ethics economics medicine knowledge |
title | Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine” |
title_full | Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine” |
title_fullStr | Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine” |
title_full_unstemmed | Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine” |
title_short | Ethics, Evidence and Economics in the Pursuit of “Personalized Medicine” |
title_sort | ethics evidence and economics in the pursuit of personalized medicine |
topic | individualized medicine pharmacology ethics economics medicine knowledge |
url | http://www.mdpi.com/2075-4426/4/2/137 |
work_keys_str_mv | AT janlewis ethicsevidenceandeconomicsinthepursuitofpersonalizedmedicine AT wendylipworth ethicsevidenceandeconomicsinthepursuitofpersonalizedmedicine AT iankerridge ethicsevidenceandeconomicsinthepursuitofpersonalizedmedicine |