Knocking out Fcgr1 of dorsal root ganglion attenuates the activation of NF-κB/NLRP3 pathway in a rat model of rheumatoid arthritis

Knocking out Fcgr1 of dorsal root ganglion attenuates the activation of NF-κB/NLRP3 pathway in a rat model of rheumatoid arthritis

Objective To explore the mechanism of peripheral neurons FcγRⅠ regulating pain caused by rheumatoid arthritis. Methods Rheumatoid arthritis models were established in 14 wild-type SD rats and 7 Fcgr1 conditional knockout rats. Wild-type rat control group (control group), rheumatoid arthritis gro...

Olles dieđut

Bibliográfalaš dieđut
Váldodahkki: LIU Fan, SU Si, WANG Tao, YUAN Bo, MA Chao
Materiálatiipa: Artihkal
Giella:zho
Almmustuhtton: Institute of Basic Medical Sciences and Peking Union Medical College Hospital, Chinese Academy of Medical Sciences / Peking Union Medical College. 2021-07-01
Ráidu:Jichu yixue yu linchuang
Fáttát:
rheumatoid arthritis|pain|central sensitization|fc-gamma receptor i (fcγrⅰ)|immune complex
Liŋkkat:http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a210300.pdf

Interneahtta

http://journal11.magtechjournal.com/Jwk_jcyxylc/fileup/1001-6325/PDF/a210300.pdf

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