Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis
Abstract Background Anemia is the most common hematological abnormality among older adults, and it is associated with decreased physical performance. But the role of hemoglobin in the absence of anemia remains unclear. Thus, this study aimed to assess the impact of hemoglobin levels on physical perf...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2022-03-01
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| Series: | BMC Geriatrics |
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| Online Access: | https://doi.org/10.1186/s12877-022-02937-4 |
| _version_ | 1818356572426862592 |
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| author | Ligiana Pires Corona Flavia Cristina Drumond Andrade Tiago da Silva Alexandre Tábatta Renata Pereira de Brito Daniella Pires Nunes Yeda Aparecida de Oliveira Duarte |
| author_facet | Ligiana Pires Corona Flavia Cristina Drumond Andrade Tiago da Silva Alexandre Tábatta Renata Pereira de Brito Daniella Pires Nunes Yeda Aparecida de Oliveira Duarte |
| author_sort | Ligiana Pires Corona |
| collection | DOAJ |
| description | Abstract Background Anemia is the most common hematological abnormality among older adults, and it is associated with decreased physical performance. But the role of hemoglobin in the absence of anemia remains unclear. Thus, this study aimed to assess the impact of hemoglobin levels on physical performance in Brazilian older adults without anemia. Methods The study is longitudinal in that it relies on two waves of the Saúde, Bem-Estar e Envelhecimento (SABE; Health, Well-being, and Aging) study: 2010 and 2015-2016. Mixed-effects linear regression was used to determine the effects of the hemoglobin concentrations on the Short Physical Performance Battery-SPPB over time among the 1,023 who had complete data and did not have anemia in 2010. In the follow-up, there were 567 without anemia. Results In analyses adjusted for age, education, comorbidities, body mass index, and physical inactivity, we found a differential association between hemoglobin concentration and SBBP by sex, with a positive interaction (β Hb*female= 0.20, 95% CI 0.04,0.37). At lower levels of hemoglobin, women have lower levels of SPPB than men, but at higher levels of hemoglobin concentration, there are no sex differences in physical performance. In addition, higher age was negatively associated with SPPB levels and cardiometabolic diseases, other diseases, and physical inactivity. Education was positively associated with physical performance. Conclusion Our study demonstrates that higher hemoglobin levels were associated with better physical performance among older adults without anemia in Brazil. However, there were sex differences in this association. This finding is important because, in clinical practice, most health professionals focus on the World Health Organization definition of anemia. Our study suggests the importance of hemoglobin levels among older adults, even those without anemia, and highlights sex differences. |
| first_indexed | 2024-12-13T19:59:21Z |
| format | Article |
| id | doaj.art-4b35909f2cba4cad8a8914a57fbcd43f |
| institution | Directory Open Access Journal |
| issn | 1471-2318 |
| language | English |
| last_indexed | 2024-12-13T19:59:21Z |
| publishDate | 2022-03-01 |
| publisher | BMC |
| record_format | Article |
| series | BMC Geriatrics |
| spelling | doaj.art-4b35909f2cba4cad8a8914a57fbcd43f2022-12-21T23:33:13ZengBMCBMC Geriatrics1471-23182022-03-012211910.1186/s12877-022-02937-4Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysisLigiana Pires Corona0Flavia Cristina Drumond Andrade1Tiago da Silva Alexandre2Tábatta Renata Pereira de Brito3Daniella Pires Nunes4Yeda Aparecida de Oliveira Duarte5Faculty of Applied Sciences, University of Campinas (UNICAMP)School of Social Work, University of Illinois at Urbana-ChampaignGerontology Department, Federal University of Sao CarlosFederal University of AlfenasMedical-surgical Nursing Area, Faculty of Nursing, University of Campinas (UNICAMP)Department of Medical-Surgical Nursing, School of Nursing, University of São PauloAbstract Background Anemia is the most common hematological abnormality among older adults, and it is associated with decreased physical performance. But the role of hemoglobin in the absence of anemia remains unclear. Thus, this study aimed to assess the impact of hemoglobin levels on physical performance in Brazilian older adults without anemia. Methods The study is longitudinal in that it relies on two waves of the Saúde, Bem-Estar e Envelhecimento (SABE; Health, Well-being, and Aging) study: 2010 and 2015-2016. Mixed-effects linear regression was used to determine the effects of the hemoglobin concentrations on the Short Physical Performance Battery-SPPB over time among the 1,023 who had complete data and did not have anemia in 2010. In the follow-up, there were 567 without anemia. Results In analyses adjusted for age, education, comorbidities, body mass index, and physical inactivity, we found a differential association between hemoglobin concentration and SBBP by sex, with a positive interaction (β Hb*female= 0.20, 95% CI 0.04,0.37). At lower levels of hemoglobin, women have lower levels of SPPB than men, but at higher levels of hemoglobin concentration, there are no sex differences in physical performance. In addition, higher age was negatively associated with SPPB levels and cardiometabolic diseases, other diseases, and physical inactivity. Education was positively associated with physical performance. Conclusion Our study demonstrates that higher hemoglobin levels were associated with better physical performance among older adults without anemia in Brazil. However, there were sex differences in this association. This finding is important because, in clinical practice, most health professionals focus on the World Health Organization definition of anemia. Our study suggests the importance of hemoglobin levels among older adults, even those without anemia, and highlights sex differences.https://doi.org/10.1186/s12877-022-02937-4HemoglobinPhysical performanceOlder adultsSABE studyBrazil |
| spellingShingle | Ligiana Pires Corona Flavia Cristina Drumond Andrade Tiago da Silva Alexandre Tábatta Renata Pereira de Brito Daniella Pires Nunes Yeda Aparecida de Oliveira Duarte Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis BMC Geriatrics Hemoglobin Physical performance Older adults SABE study Brazil |
| title | Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis |
| title_full | Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis |
| title_fullStr | Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis |
| title_full_unstemmed | Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis |
| title_short | Higher hemoglobin levels are associated with better physical performance among older adults without anemia: a longitudinal analysis |
| title_sort | higher hemoglobin levels are associated with better physical performance among older adults without anemia a longitudinal analysis |
| topic | Hemoglobin Physical performance Older adults SABE study Brazil |
| url | https://doi.org/10.1186/s12877-022-02937-4 |
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