Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites

Lapatinib, Nilotinib and Lomitapide Inhibit Haemozoin Formation in Malaria Parasites

With the continued loss of antimalarials to resistance, drug repositioning may have a role in maximising efficiency and accelerating the discovery of new antimalarial drugs. Bayesian statistics was previously used as a tool to virtually screen USFDA approved drugs for predicted β-haematin (synthetic...

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Bibliographic Details
Main Authors: Ana Carolina C. de Sousa, Keletso Maepa, Jill M. Combrinck, Timothy J. Egan
Format: Article
Language:English
Published: MDPI AG 2020-03-01
Series:Molecules
Subjects:
β-haematin
haemozoin
virtual screening
docking
drug repurposing
<i>Plasmodium</i>
Online Access:https://www.mdpi.com/1420-3049/25/7/1571

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