308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor
Background Pityriasis Versicolor (PV) is known as a superficial fungal infection. It is suggested that resistant strains to azoles may be developed and hence, the treatment would be difficult. This study aimed to evaluate the efficacy of excimer laser (308 nm) as an alternative therapy for PV. Mater...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Taylor & Francis Group
2021-10-01
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| Series: | Journal of Dermatological Treatment |
| Subjects: | |
| Online Access: | http://dx.doi.org/10.1080/09546634.2020.1713972 |
| _version_ | 1797683600198467584 |
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| author | Fathia M. Khattab Farida H. Omran |
| author_facet | Fathia M. Khattab Farida H. Omran |
| author_sort | Fathia M. Khattab |
| collection | DOAJ |
| description | Background Pityriasis Versicolor (PV) is known as a superficial fungal infection. It is suggested that resistant strains to azoles may be developed and hence, the treatment would be difficult. This study aimed to evaluate the efficacy of excimer laser (308 nm) as an alternative therapy for PV. Materials and methods This is a prospective intra-patient left-to-right, randomized, placebo-controlled study conducted on 26 patients with bilateral lesions which are not responding to the PV standard treatment. Patients were randomly assigned to right or left-side therapy for a duration of 8 weeks with either excimer laser (308 nm three times weekly) or topical placebo. Clinical assessment and mycological evaluation were performed before the initiation of treatment and at the fourth and eighth week of therapy. Results A decrease in the mean clinical score of cases was recorded from 7.1 at the baseline evaluation to 1.56 after 4 weeks and to 1.96 after 8 weeks of treatment. At week 4, there was a statistically significant reduction in the clinical scores compared with pretreatment scores and with the placebo group (p < .001). Conclusion 308-nm excimer laser can be considered as a hopeful and optional therapy for PV. |
| first_indexed | 2024-03-12T00:17:56Z |
| format | Article |
| id | doaj.art-4b3929e40dd242afb81142d2d8de906f |
| institution | Directory Open Access Journal |
| issn | 0954-6634 1471-1753 |
| language | English |
| last_indexed | 2024-03-12T00:17:56Z |
| publishDate | 2021-10-01 |
| publisher | Taylor & Francis Group |
| record_format | Article |
| series | Journal of Dermatological Treatment |
| spelling | doaj.art-4b3929e40dd242afb81142d2d8de906f2023-09-15T14:23:04ZengTaylor & Francis GroupJournal of Dermatological Treatment0954-66341471-17532021-10-0132779579910.1080/09546634.2020.17139721713972308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolorFathia M. Khattab0Farida H. Omran1Department of Dermatology, Venereology, and Andrology, Faculty of Medicine, Zagazig UniversityDepartment of Microbiology, Faculty of Medicine, Zagazig UniversityBackground Pityriasis Versicolor (PV) is known as a superficial fungal infection. It is suggested that resistant strains to azoles may be developed and hence, the treatment would be difficult. This study aimed to evaluate the efficacy of excimer laser (308 nm) as an alternative therapy for PV. Materials and methods This is a prospective intra-patient left-to-right, randomized, placebo-controlled study conducted on 26 patients with bilateral lesions which are not responding to the PV standard treatment. Patients were randomly assigned to right or left-side therapy for a duration of 8 weeks with either excimer laser (308 nm three times weekly) or topical placebo. Clinical assessment and mycological evaluation were performed before the initiation of treatment and at the fourth and eighth week of therapy. Results A decrease in the mean clinical score of cases was recorded from 7.1 at the baseline evaluation to 1.56 after 4 weeks and to 1.96 after 8 weeks of treatment. At week 4, there was a statistically significant reduction in the clinical scores compared with pretreatment scores and with the placebo group (p < .001). Conclusion 308-nm excimer laser can be considered as a hopeful and optional therapy for PV.http://dx.doi.org/10.1080/09546634.2020.1713972pityriasis versicolortherapyexcimer laser |
| spellingShingle | Fathia M. Khattab Farida H. Omran 308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor Journal of Dermatological Treatment pityriasis versicolor therapy excimer laser |
| title | 308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor |
| title_full | 308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor |
| title_fullStr | 308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor |
| title_full_unstemmed | 308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor |
| title_short | 308-nm excimer laser: a hopeful and optional therapy for pityriasis versicolor |
| title_sort | 308 nm excimer laser a hopeful and optional therapy for pityriasis versicolor |
| topic | pityriasis versicolor therapy excimer laser |
| url | http://dx.doi.org/10.1080/09546634.2020.1713972 |
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