MgADP Promotes Myosin Head Movement toward Actin at Low [Ca<sup>2+</sup>] to Increase Force Production and Ca<sup>2+</sup>-Sensitivity of Contraction in Permeabilized Porcine Myocardial Strips
Myosin cross-bridges dissociate from actin following Mg<sup>2+</sup>-adenosine triphosphate (MgATP) binding. Myosin hydrolyses MgATP into inorganic phosphate (P<sub>i</sub>) and Mg<sup>2+</sup>-adenosine diphosphate (ADP), and release of these hydrolysis products...
Main Authors: | Peter O. Awinda, Weikang Ma, Kyrah L. Turner, Jing Zhao, Henry Gong, Mindy S. Thompson, Kenneth S. Campbell, Thomas C. Irving, Bertrand C. W. Tanner |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2022-12-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | https://www.mdpi.com/1422-0067/23/23/15084 |
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