Characteristics of symptom burden in atrial fibrillation with concomitant heart failure
Abstract Background Symptom burden is an important factor in determining the treatment of atrial fibrillation (AF). AF is frequently accompanied by heart failure (HF). This study investigated the characteristics of AF symptoms with concomitant HF. Methods A total of 4885 patients with AF were consec...
| Main Authors: | , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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BMC
2020-01-01
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| Series: | International Journal of Arrhythmia |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s42444-019-0009-9 |
| _version_ | 1818949540708876288 |
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| author | Ran Heo Myung-Jin Cha Tae-Hoon Kim Jung Myung Lee Junbeom Park Hyung Wook Park Ki-Woon Kang Jaemin Shim Jae-Sun Uhm Jun Kim Jin-Bae Kim Changsoo Kim Young Soo Lee Eue-Keun Choi Boyoung Joung Jin-Kyu Park |
| author_facet | Ran Heo Myung-Jin Cha Tae-Hoon Kim Jung Myung Lee Junbeom Park Hyung Wook Park Ki-Woon Kang Jaemin Shim Jae-Sun Uhm Jun Kim Jin-Bae Kim Changsoo Kim Young Soo Lee Eue-Keun Choi Boyoung Joung Jin-Kyu Park |
| author_sort | Ran Heo |
| collection | DOAJ |
| description | Abstract Background Symptom burden is an important factor in determining the treatment of atrial fibrillation (AF). AF is frequently accompanied by heart failure (HF). This study investigated the characteristics of AF symptoms with concomitant HF. Methods A total of 4885 patients with AF were consecutively enrolled through a prospective observational registry (the Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation [CODE-AF] registry). Clinically diagnosed HF was divided into three categories (preserved, mid-range, and reduced ejection fraction [EF]). Symptom severity was assessed using the European Heart Rhythm Association (EHRA) classification. Results The presence of AF-related symptoms was comparable irrespective of concomitant HF. Patients with HF with reduced EF demonstrated severe (EHRA classes 3 and 4) and atypical symptoms. HF with preserved EF was also associated with atypical symptoms. Female sex and AF type were associated with the presence of symptoms in AF without HF, and non-maintenance of sinus rhythm and increased left atrial pressure (E/e′ ≥ 15) were factors related to the presence of symptoms in AF with HF. Conclusion AF with concomitant HF presented with more severe and atypical symptoms than AF without HF. Maintaining the sinus rhythm and reducing the E/e’ ratio are important factors for reducing symptoms in AF with concomitant HF. |
| first_indexed | 2024-12-20T09:04:19Z |
| format | Article |
| id | doaj.art-4b3f5721404e45b994158f86a1904388 |
| institution | Directory Open Access Journal |
| issn | 2466-1171 |
| language | English |
| last_indexed | 2024-12-20T09:04:19Z |
| publishDate | 2020-01-01 |
| publisher | BMC |
| record_format | Article |
| series | International Journal of Arrhythmia |
| spelling | doaj.art-4b3f5721404e45b994158f86a19043882022-12-21T19:45:46ZengBMCInternational Journal of Arrhythmia2466-11712020-01-012111810.1186/s42444-019-0009-9Characteristics of symptom burden in atrial fibrillation with concomitant heart failureRan Heo0Myung-Jin Cha1Tae-Hoon Kim2Jung Myung Lee3Junbeom Park4Hyung Wook Park5Ki-Woon Kang6Jaemin Shim7Jae-Sun Uhm8Jun Kim9Jin-Bae Kim10Changsoo Kim11Young Soo Lee12Eue-Keun Choi13Boyoung Joung14Jin-Kyu Park15Department of Cardiology, Hanyang University Medical Center, Hanyang University Seoul HospitalDepartment of Internal Medicine, Seoul National University HospitalDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of MedicineDivision of Cardiology, Department of Internal Medicine, Kyung Hee University Hospital, Kyung Hee UniversityDepartment of Cardiology, School of Medicine, Ewha Womans UniversityDepartment of Cardiology, Chonnam National University Hospital, Chonnam National University School of MedicineDivision of Cardiology, Eulji University HospitalDivision of Cardiology, Department of Internal Medicine, Korea University Medical CenterDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of MedicineHeart Institute, Asan Medical Center, University of Ulsan College of MedicineDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of MedicineDepartment of Preventive Medicine, Institute of Human Complexity and Systems Science, Yonsei University College of MedicineDivision of Cardiology, Department of Internal Medicine, Daegu Catholic University Medical CenterDepartment of Internal Medicine, Seoul National University HospitalDivision of Cardiology, Department of Internal Medicine, Severance Cardiovascular Hospital, Yonsei University College of MedicineDepartment of Cardiology, Hanyang University Medical Center, Hanyang University Seoul HospitalAbstract Background Symptom burden is an important factor in determining the treatment of atrial fibrillation (AF). AF is frequently accompanied by heart failure (HF). This study investigated the characteristics of AF symptoms with concomitant HF. Methods A total of 4885 patients with AF were consecutively enrolled through a prospective observational registry (the Comparison Study of Drugs for Symptom Control and Complication Prevention of Atrial Fibrillation [CODE-AF] registry). Clinically diagnosed HF was divided into three categories (preserved, mid-range, and reduced ejection fraction [EF]). Symptom severity was assessed using the European Heart Rhythm Association (EHRA) classification. Results The presence of AF-related symptoms was comparable irrespective of concomitant HF. Patients with HF with reduced EF demonstrated severe (EHRA classes 3 and 4) and atypical symptoms. HF with preserved EF was also associated with atypical symptoms. Female sex and AF type were associated with the presence of symptoms in AF without HF, and non-maintenance of sinus rhythm and increased left atrial pressure (E/e′ ≥ 15) were factors related to the presence of symptoms in AF with HF. Conclusion AF with concomitant HF presented with more severe and atypical symptoms than AF without HF. Maintaining the sinus rhythm and reducing the E/e’ ratio are important factors for reducing symptoms in AF with concomitant HF.https://doi.org/10.1186/s42444-019-0009-9Symptom burdenAtrial fibrillationHeart failure |
| spellingShingle | Ran Heo Myung-Jin Cha Tae-Hoon Kim Jung Myung Lee Junbeom Park Hyung Wook Park Ki-Woon Kang Jaemin Shim Jae-Sun Uhm Jun Kim Jin-Bae Kim Changsoo Kim Young Soo Lee Eue-Keun Choi Boyoung Joung Jin-Kyu Park Characteristics of symptom burden in atrial fibrillation with concomitant heart failure International Journal of Arrhythmia Symptom burden Atrial fibrillation Heart failure |
| title | Characteristics of symptom burden in atrial fibrillation with concomitant heart failure |
| title_full | Characteristics of symptom burden in atrial fibrillation with concomitant heart failure |
| title_fullStr | Characteristics of symptom burden in atrial fibrillation with concomitant heart failure |
| title_full_unstemmed | Characteristics of symptom burden in atrial fibrillation with concomitant heart failure |
| title_short | Characteristics of symptom burden in atrial fibrillation with concomitant heart failure |
| title_sort | characteristics of symptom burden in atrial fibrillation with concomitant heart failure |
| topic | Symptom burden Atrial fibrillation Heart failure |
| url | https://doi.org/10.1186/s42444-019-0009-9 |
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