Homing of mRNA-Modified Endothelial Progenitor Cells to Inflamed Endothelium

Homing of mRNA-Modified Endothelial Progenitor Cells to Inflamed Endothelium

Endothelial progenitor cells (EPCs) are one of the most important stem cells for the neovascularization of tissues damaged by ischemic diseases such as myocardial infarction, ischemic stroke, or critical limb ischemia. However, their low homing efficiency in the treatment of ischemic tissues limits...

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Bibliographic Details
Main Authors: Denis Canjuga, Heidrun Steinle, Jana Mayer, Ann-Kristin Uhde, Gerd Klein, Hans Peter Wendel, Christian Schlensak, Meltem Avci-Adali
Format: Article
Language:English
Published: MDPI AG 2022-06-01
Series:Pharmaceutics
Subjects:
synthetic mRNA
EPCs
homing
engineering
angiogenesis
endothelium
Online Access:https://www.mdpi.com/1999-4923/14/6/1194

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