GATA4 Is Required for Budding Morphogenesis of Posterior Foregut Endoderm in a Model of Human Stomach Development

GATA4 Is Required for Budding Morphogenesis of Posterior Foregut Endoderm in a Model of Human Stomach Development

Three-dimensional gastrointestinal organoid culture systems provide innovative and tractable models to investigate fundamental developmental biology questions using human cells. The goal of this study was to explore the role of the zinc-finger containing transcription factor GATA4 in gastric develop...

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Bibliographic Details
Main Authors: Ann DeLaForest, Afiya F. Quryshi, Talia S. Frolkis, Olivia D. Franklin, Michele A. Battle
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Medicine
Subjects:
gastric development
GATA4
stem cell models
endoderm
morphogenesis
Online Access:https://www.frontiersin.org/article/10.3389/fmed.2020.00044/full

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