Spatial control of irreversible protein aggregation

Liquid cellular compartments form in the cyto- or nucleoplasm and can regulate aberrant protein aggregation. Yet, the mechanisms by which these compartments affect protein aggregation remain unknown. Here, we combine kinetic theory of protein aggregation and liquid-liquid phase separation to study t...

Πλήρης περιγραφή

Λεπτομέρειες βιβλιογραφικής εγγραφής
Κύριοι συγγραφείς: Christoph Weber, Thomas Michaels, L Mahadevan
Μορφή: Άρθρο
Γλώσσα:English
Έκδοση: eLife Sciences Publications Ltd 2019-05-01
Σειρά:eLife
Θέματα:
Διαθέσιμο Online:https://elifesciences.org/articles/42315