What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure

Abstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. T...

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Bibliographic Details
Main Authors: Nicola Amelotti, Massimo Mapelli, Marco Guglielmo, Maria Inês Fiuza Branco Pires, Jeness Campodonico, Benedetta Majocchi, Valentina Ribatti, Giulia Vettor, Andrea Baggiano, Valentina Catto, Cristina Basso, Gianluca Pontone, Piergiuseppe Agostoni
Format: Article
Language:English
Published: Wiley 2023-02-01
Series:ESC Heart Failure
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Online Access:https://doi.org/10.1002/ehf2.14172
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Summary:Abstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started.
ISSN:2055-5822