What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure
Abstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. T...
| Main Authors: | , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Wiley
2023-02-01
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| Series: | ESC Heart Failure |
| Subjects: | |
| Online Access: | https://doi.org/10.1002/ehf2.14172 |
| _version_ | 1797944752182657024 |
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| author | Nicola Amelotti Massimo Mapelli Marco Guglielmo Maria Inês Fiuza Branco Pires Jeness Campodonico Benedetta Majocchi Valentina Ribatti Giulia Vettor Andrea Baggiano Valentina Catto Cristina Basso Gianluca Pontone Piergiuseppe Agostoni |
| author_facet | Nicola Amelotti Massimo Mapelli Marco Guglielmo Maria Inês Fiuza Branco Pires Jeness Campodonico Benedetta Majocchi Valentina Ribatti Giulia Vettor Andrea Baggiano Valentina Catto Cristina Basso Gianluca Pontone Piergiuseppe Agostoni |
| author_sort | Nicola Amelotti |
| collection | DOAJ |
| description | Abstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started. |
| first_indexed | 2024-04-10T20:44:37Z |
| format | Article |
| id | doaj.art-4b4fc40de8fc4e5ba08f3689c506705f |
| institution | Directory Open Access Journal |
| issn | 2055-5822 |
| language | English |
| last_indexed | 2024-04-10T20:44:37Z |
| publishDate | 2023-02-01 |
| publisher | Wiley |
| record_format | Article |
| series | ESC Heart Failure |
| spelling | doaj.art-4b4fc40de8fc4e5ba08f3689c506705f2023-01-24T09:02:17ZengWileyESC Heart Failure2055-58222023-02-0110170971510.1002/ehf2.14172What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failureNicola Amelotti0Massimo Mapelli1Marco Guglielmo2Maria Inês Fiuza Branco Pires3Jeness Campodonico4Benedetta Majocchi5Valentina Ribatti6Giulia Vettor7Andrea Baggiano8Valentina Catto9Cristina Basso10Gianluca Pontone11Piergiuseppe Agostoni12Heart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyUniversity Medical Centre Utrecht Utrecht The NetherlandsCentro Hospitalar Tondela‐Viseu Viseu PortugalHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyDepartment of Cardiac, Thoracic and Vascular Sciences and Public Health University of Padua Padua ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyHeart Failure Unit Centro Cardiologico Monzino, IRCCS Milan ItalyAbstract Eosinophilic granulomatosis with polyangiitis (EGPA) is a rare multisystem disorder; cardiac involvement may include eosinophilic myocarditis. A 67‐year‐old woman presented with 1‐week history of dyspnoea and orthopnoea. She had a history of adult‐onset asthma and peripheral eosinophilia. The investigations showed T‐wave inversion on lateral leads, peripheral eosinophilia, elevated troponin and BNP values, and severe biventricular systolic dysfunction with diffuse hypokinesia and apical akinesia. Computed tomography excluded coronary disease and showed bilateral basal ground‐glass opacities, air‐space consolidation, and bilateral reticular‐nodular pattern. Cardiac magnetic resonance findings were compatible with active myocardial inflammation. An endomyocardial biopsy (EMB) confirmed the diagnosis of eosinophilic myocarditis, and a therapy with oral corticosteroids and heart failure medications was started.https://doi.org/10.1002/ehf2.14172Eosinophilic granulomatosis with polyangiitis (Churg–Strauss)Eosinophilic myocarditisHeart failureEndomyocardial biopsyCardiac magnetic resonance |
| spellingShingle | Nicola Amelotti Massimo Mapelli Marco Guglielmo Maria Inês Fiuza Branco Pires Jeness Campodonico Benedetta Majocchi Valentina Ribatti Giulia Vettor Andrea Baggiano Valentina Catto Cristina Basso Gianluca Pontone Piergiuseppe Agostoni What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure ESC Heart Failure Eosinophilic granulomatosis with polyangiitis (Churg–Strauss) Eosinophilic myocarditis Heart failure Endomyocardial biopsy Cardiac magnetic resonance |
| title | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
| title_full | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
| title_fullStr | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
| title_full_unstemmed | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
| title_short | What's behind your eosinophilic myocarditis? A case of Churg–Strauss syndrome diagnosed during acute heart failure |
| title_sort | what s behind your eosinophilic myocarditis a case of churg strauss syndrome diagnosed during acute heart failure |
| topic | Eosinophilic granulomatosis with polyangiitis (Churg–Strauss) Eosinophilic myocarditis Heart failure Endomyocardial biopsy Cardiac magnetic resonance |
| url | https://doi.org/10.1002/ehf2.14172 |
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