Molecular mechanisms of Agardhiella subulata attenuates hepatic fibrosis by modulating hepatic stellate cell activation via the reduction of autophagy

Molecular mechanisms of Agardhiella subulata attenuates hepatic fibrosis by modulating hepatic stellate cell activation via the reduction of autophagy

In this study, we investigated the effects of Agardhiella subulata extract (ASE) and its underlying mechanisms in vivo and in vitro. Rats induced hepatic fibrosis with CCl4 and transforming growth factor-β1 (TGF-β1) activated rat hepatic stellate cell line (HSC-T6) was used. The results showed that...

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Bibliographic Details
Main Authors: Choirul Anwar, Mei-Ling Tsai, Bio-Nain Chen, Li-Yun Hsu, Ching-Shu Lai
Format: Article
Language:English
Published: Elsevier 2022-09-01
Series:Journal of Functional Foods
Subjects:
Agardhiella subulata
Autophagy
Lipid droplet
Hepatic stellate cell
Hepatic fibrosis
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464622002961

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