Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited
Tailoring medical treatment to individual patients requires a strong foundation in research to provide the data necessary to understand the relationship between the disease, the patient, and the type of treatment advocated for. Non-therapeutic oncology clinical trials studying therapeutic resistance...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2013-03-01
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| Series: | Frontiers in Pharmacology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00025/full |
| _version_ | 1819274977781743616 |
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| author | Lee eBlack Gerald eBatist Denise eAvard Caroline eRousseau Zuanel eDiaz Bartha Maria Knoppers |
| author_facet | Lee eBlack Gerald eBatist Denise eAvard Caroline eRousseau Zuanel eDiaz Bartha Maria Knoppers |
| author_sort | Lee eBlack |
| collection | DOAJ |
| description | Tailoring medical treatment to individual patients requires a strong foundation in research to provide the data necessary to understand the relationship between the disease, the patient, and the type of treatment advocated for. Non-therapeutic oncology clinical trials studying therapeutic resistance require the participation of patients, yet only a small percentage enroll. Treating physicians are often relied on to recruit patients, but they have a number of ethical obligations that might be perceived as barriers to recruiting. Concepts such as voluntariness of consent and conflicts of interest can have an impact on whether physicians will discuss clinical trials with their patients and how patients perceive the information. However, these ethical obligations should not be prohibitive to physician recruitment of patients—precautions can be taken to ensure that patients’ consent to research participation is fully voluntary and devoid of conflict, such as the use of other members of the research team than the treating physician to discuss the trial and obtain consent, and better communication between researchers, clinicians and patients. These can ensure that research benefits are maximized for the good of patients and society. |
| first_indexed | 2024-12-23T23:17:00Z |
| format | Article |
| id | doaj.art-4b5507cb3a914adebc8f4bd7a13cfaa6 |
| institution | Directory Open Access Journal |
| issn | 1663-9812 |
| language | English |
| last_indexed | 2024-12-23T23:17:00Z |
| publishDate | 2013-03-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Pharmacology |
| spelling | doaj.art-4b5507cb3a914adebc8f4bd7a13cfaa62022-12-21T17:26:29ZengFrontiers Media S.A.Frontiers in Pharmacology1663-98122013-03-01410.3389/fphar.2013.0002542298Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisitedLee eBlack0Gerald eBatist1Denise eAvard2Caroline eRousseau3Zuanel eDiaz4Bartha Maria Knoppers5McGill UniversityMcGill University Centre for Translational Research in CancerMcGill UniversityQuebec Clinical Research Organization in Cancer (Q-CROC)Quebec Clinical Research Organization in Cancer (Q-CROC)McGill UniversityTailoring medical treatment to individual patients requires a strong foundation in research to provide the data necessary to understand the relationship between the disease, the patient, and the type of treatment advocated for. Non-therapeutic oncology clinical trials studying therapeutic resistance require the participation of patients, yet only a small percentage enroll. Treating physicians are often relied on to recruit patients, but they have a number of ethical obligations that might be perceived as barriers to recruiting. Concepts such as voluntariness of consent and conflicts of interest can have an impact on whether physicians will discuss clinical trials with their patients and how patients perceive the information. However, these ethical obligations should not be prohibitive to physician recruitment of patients—precautions can be taken to ensure that patients’ consent to research participation is fully voluntary and devoid of conflict, such as the use of other members of the research team than the treating physician to discuss the trial and obtain consent, and better communication between researchers, clinicians and patients. These can ensure that research benefits are maximized for the good of patients and society.http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00025/fullConflict of InterestEthicsInformed ConsentClinical Trialrecruitment |
| spellingShingle | Lee eBlack Gerald eBatist Denise eAvard Caroline eRousseau Zuanel eDiaz Bartha Maria Knoppers Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited Frontiers in Pharmacology Conflict of Interest Ethics Informed Consent Clinical Trial recruitment |
| title | Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited |
| title_full | Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited |
| title_fullStr | Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited |
| title_full_unstemmed | Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited |
| title_short | Physician recruitment of patients to non-therapeutic oncology clinical trials: ethics revisited |
| title_sort | physician recruitment of patients to non therapeutic oncology clinical trials ethics revisited |
| topic | Conflict of Interest Ethics Informed Consent Clinical Trial recruitment |
| url | http://journal.frontiersin.org/Journal/10.3389/fphar.2013.00025/full |
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