Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome

The patient is a 70-year-old male with no other atherogenic risk factors who presented with an acute coronary syndrome (ACS) of unstable angina subsequently complicated by a non-ST elevation myocardial infarction (NSTEMI). The patient’s presentation posed 3 unique features: (1) cardiac catheterizati...

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Main Authors: Wesam Ostwani MD, Holly Fleming MD, Carlos A. Roldan MD
Format: Article
Language:English
Published: SAGE Publishing 2016-03-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/2324709616640008
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author Wesam Ostwani MD
Holly Fleming MD
Carlos A. Roldan MD
author_facet Wesam Ostwani MD
Holly Fleming MD
Carlos A. Roldan MD
author_sort Wesam Ostwani MD
collection DOAJ
description The patient is a 70-year-old male with no other atherogenic risk factors who presented with an acute coronary syndrome (ACS) of unstable angina subsequently complicated by a non-ST elevation myocardial infarction (NSTEMI). The patient’s presentation posed 3 unique features: (1) cardiac catheterization demonstrated nonobstructive 3-vessel multi-aneurysmal coronary artery disease with sluggish antegrade coronary flow; (2) a nonobstructive aneurysmal dissection flap based on contrast staining of the mid left anterior descending artery, which may have led to in situ nonocclusive thrombosis and distal microvascular embolization; and (3) successful conservative medical therapy of coronary artery aneurysmal disease (CAAD) complicated with ACS. CAAD has an incidence of 1.5% to 4.9% in adults. The most common etiology of CAAD is atherosclerotic coronary artery disease. There are no guidelines for the management of CAAD complicated by ACS, and controversies exist as to whether conservative, catheter-based, or surgical management should be pursued.
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spelling doaj.art-4b565eb85a254c92a1f20b78ddf180772022-12-21T19:59:55ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962016-03-01410.1177/232470961664000810.1177_2324709616640008Coronary Artery Aneurysmal Disease and Acute Coronary SyndromeWesam Ostwani MD0Holly Fleming MD1Carlos A. Roldan MD2University of New Mexico, Albuquerque, NM, USANew Mexico VA Health Care System, Albuquerque, NM, USANew Mexico VA Health Care System, Albuquerque, NM, USAThe patient is a 70-year-old male with no other atherogenic risk factors who presented with an acute coronary syndrome (ACS) of unstable angina subsequently complicated by a non-ST elevation myocardial infarction (NSTEMI). The patient’s presentation posed 3 unique features: (1) cardiac catheterization demonstrated nonobstructive 3-vessel multi-aneurysmal coronary artery disease with sluggish antegrade coronary flow; (2) a nonobstructive aneurysmal dissection flap based on contrast staining of the mid left anterior descending artery, which may have led to in situ nonocclusive thrombosis and distal microvascular embolization; and (3) successful conservative medical therapy of coronary artery aneurysmal disease (CAAD) complicated with ACS. CAAD has an incidence of 1.5% to 4.9% in adults. The most common etiology of CAAD is atherosclerotic coronary artery disease. There are no guidelines for the management of CAAD complicated by ACS, and controversies exist as to whether conservative, catheter-based, or surgical management should be pursued.https://doi.org/10.1177/2324709616640008
spellingShingle Wesam Ostwani MD
Holly Fleming MD
Carlos A. Roldan MD
Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome
Journal of Investigative Medicine High Impact Case Reports
title Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome
title_full Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome
title_fullStr Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome
title_full_unstemmed Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome
title_short Coronary Artery Aneurysmal Disease and Acute Coronary Syndrome
title_sort coronary artery aneurysmal disease and acute coronary syndrome
url https://doi.org/10.1177/2324709616640008
work_keys_str_mv AT wesamostwanimd coronaryarteryaneurysmaldiseaseandacutecoronarysyndrome
AT hollyflemingmd coronaryarteryaneurysmaldiseaseandacutecoronarysyndrome
AT carlosaroldanmd coronaryarteryaneurysmaldiseaseandacutecoronarysyndrome