Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study

Objective: To explore potential risk factors of postoperative nausea and vomiting (PONV) following ambulatory surgery. Method: Clinical data of 1670 cases receiving ambulatory surgery in Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School from September 2017 to...

Full description

Bibliographic Details
Main Authors: Yue Qian, Jian-kun Zhu, Bai-ling Hou, Yu-e Sun, Xiao-ping Gu, Zheng-liang Ma
Format: Article
Language:English
Published: Elsevier 2022-12-01
Series:Heliyon
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2405844022037185
_version_ 1797960802804695040
author Yue Qian
Jian-kun Zhu
Bai-ling Hou
Yu-e Sun
Xiao-ping Gu
Zheng-liang Ma
author_facet Yue Qian
Jian-kun Zhu
Bai-ling Hou
Yu-e Sun
Xiao-ping Gu
Zheng-liang Ma
author_sort Yue Qian
collection DOAJ
description Objective: To explore potential risk factors of postoperative nausea and vomiting (PONV) following ambulatory surgery. Method: Clinical data of 1670 cases receiving ambulatory surgery in Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School from September 2017 to December 2019 were retrospectively analyzed. They were categorized to PONV group and non-PONV group, and perioperative data in both groups were analyzed for assessing risk factors of PONV following ambulatory laparoscopy. Results: There were 156/1,670 (9.3%) PONV cases, and the female and male incidence in recruited cases was 12.0% and 6.0%, respectively. Analyses on perioperative data of them identified that female gender [adjusted odds ratio (aOR) = 2.060, P < 0.001], operation time >1 h (aOR = 1.554, P = 0.011), postoperative pain at rest (aOR = 1.909, P = 0.013) and postoperative pain during activities (aOR = 3.512, P < 0.001) were independent risk factors of PONV following ambulatory surgery. Furthermore, postoperative pain at rest and during activities were linearly, positively correlated to the incidence of PONV. Conclusion: Female gender, operation time >1 h and postoperative pain are closely related with the incidence of PONV following ambulatory surgery. Alleviating postoperative pain properly is one of the methods to reduce risk factors of PONV following ambulatory surgery.
first_indexed 2024-04-11T00:51:01Z
format Article
id doaj.art-4b590dad01f44434aacff00bb20c7f41
institution Directory Open Access Journal
issn 2405-8440
language English
last_indexed 2024-04-11T00:51:01Z
publishDate 2022-12-01
publisher Elsevier
record_format Article
series Heliyon
spelling doaj.art-4b590dad01f44434aacff00bb20c7f412023-01-05T08:40:25ZengElsevierHeliyon2405-84402022-12-01812e12430Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control studyYue Qian0Jian-kun Zhu1Bai-ling Hou2Yu-e Sun3Xiao-ping Gu4Zheng-liang Ma5Department of Anesthesiology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Anesthesiology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, ChinaDepartment of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, ChinaDepartment of Anesthesiology, Nanjing Drum Tower Hospital, The Affiliated Hospital of Nanjing University Medical School, Nanjing, ChinaDepartment of Anesthesiology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China; Corresponding author.Department of Anesthesiology, Nanjing Drum Tower Hospital, Clinical College of Nanjing Medical University, Nanjing, China; Corresponding author.Objective: To explore potential risk factors of postoperative nausea and vomiting (PONV) following ambulatory surgery. Method: Clinical data of 1670 cases receiving ambulatory surgery in Nanjing Drum Tower Hospital, the Affiliated Hospital of Nanjing University Medical School from September 2017 to December 2019 were retrospectively analyzed. They were categorized to PONV group and non-PONV group, and perioperative data in both groups were analyzed for assessing risk factors of PONV following ambulatory laparoscopy. Results: There were 156/1,670 (9.3%) PONV cases, and the female and male incidence in recruited cases was 12.0% and 6.0%, respectively. Analyses on perioperative data of them identified that female gender [adjusted odds ratio (aOR) = 2.060, P < 0.001], operation time >1 h (aOR = 1.554, P = 0.011), postoperative pain at rest (aOR = 1.909, P = 0.013) and postoperative pain during activities (aOR = 3.512, P < 0.001) were independent risk factors of PONV following ambulatory surgery. Furthermore, postoperative pain at rest and during activities were linearly, positively correlated to the incidence of PONV. Conclusion: Female gender, operation time >1 h and postoperative pain are closely related with the incidence of PONV following ambulatory surgery. Alleviating postoperative pain properly is one of the methods to reduce risk factors of PONV following ambulatory surgery.http://www.sciencedirect.com/science/article/pii/S2405844022037185Postoperative nausea and vomitingAmbulatory surgeryPostoperative pain
spellingShingle Yue Qian
Jian-kun Zhu
Bai-ling Hou
Yu-e Sun
Xiao-ping Gu
Zheng-liang Ma
Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study
Heliyon
Postoperative nausea and vomiting
Ambulatory surgery
Postoperative pain
title Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study
title_full Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study
title_fullStr Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study
title_full_unstemmed Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study
title_short Risk factors of postoperative nausea and vomiting following ambulatory surgery: A retrospective case-control study
title_sort risk factors of postoperative nausea and vomiting following ambulatory surgery a retrospective case control study
topic Postoperative nausea and vomiting
Ambulatory surgery
Postoperative pain
url http://www.sciencedirect.com/science/article/pii/S2405844022037185
work_keys_str_mv AT yueqian riskfactorsofpostoperativenauseaandvomitingfollowingambulatorysurgeryaretrospectivecasecontrolstudy
AT jiankunzhu riskfactorsofpostoperativenauseaandvomitingfollowingambulatorysurgeryaretrospectivecasecontrolstudy
AT bailinghou riskfactorsofpostoperativenauseaandvomitingfollowingambulatorysurgeryaretrospectivecasecontrolstudy
AT yuesun riskfactorsofpostoperativenauseaandvomitingfollowingambulatorysurgeryaretrospectivecasecontrolstudy
AT xiaopinggu riskfactorsofpostoperativenauseaandvomitingfollowingambulatorysurgeryaretrospectivecasecontrolstudy
AT zhengliangma riskfactorsofpostoperativenauseaandvomitingfollowingambulatorysurgeryaretrospectivecasecontrolstudy