Enhancing Pharmacokinetics and Pharmacodynamics of Rosuvastatin Calcium through the Development and Optimization of Fast-Dissolving Films

Enhancing Pharmacokinetics and Pharmacodynamics of Rosuvastatin Calcium through the Development and Optimization of Fast-Dissolving Films

Rosuvastatin (RSV) is a widely used cholesterol-lowering medication, but its limited bioavailability due to its susceptibility to stomach pH and extensive first-pass metabolism poses a significant challenge. A fast-dissolving film (FDF) formulation of RSV was developed, characterized, and compared t...

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Bibliographic Details
Main Authors:	Ibrahim Ashraf, Pierre A. Hanna, Shadeed Gad, Fathy I. Abd-Allah, Khalid M. El-Say
Format:	Article
Language:	English
Published:	MDPI AG 2023-11-01
Series:	Pharmaceutics
Subjects:	fast-dissolving film rosuvastatin pharmacokinetics hyperlipidemia design of experiment approach
Online Access:	https://www.mdpi.com/1999-4923/15/11/2640

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