Evolution and Development of the Inner Ear Efferent System: Transforming a Motor Neuron Population to Connect to the Most Unusual Motor Protein via Ancient Nicotinic Receptors

Evolution and Development of the Inner Ear Efferent System: Transforming a Motor Neuron Population to Connect to the Most Unusual Motor Protein via Ancient Nicotinic Receptors

All craniate chordates have inner ears with hair cells that receive input from the brain by cholinergic centrifugal fibers, the so-called inner ear efferents (IEEs). Comparative data suggest that IEEs derive from facial branchial motor (FBM) neurons that project to the inner ear instead of facial mu...

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Bibliographic Details
Main Authors: Bernd Fritzsch, Karen L. Elliott
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Cellular Neuroscience
Subjects:
ear
development
evolution
efferents
facial branchial motor neurons
nicotinic receptors
Online Access:http://journal.frontiersin.org/article/10.3389/fncel.2017.00114/full

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