Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis
ABSTRACT: Purpose: To investigate visual-related quality of life (VRQL) and prevalence and severity of depressive symptoms in Brazilian individuals with toxoplasmic retinochoroiditis (TRC). Design: Comparative observational cross-sectional study. The National Eye Institute Visual Function Questionn...
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| Format: | Article |
| Language: | English |
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Elsevier
2021-11-01
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| Series: | International Journal of Infectious Diseases |
| Subjects: | |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S1201971221006858 |
| _version_ | 1818342988122685440 |
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| author | Jacqueline Souza Dutra Arruda Jacqueline Domingues Tibúrcio Salvina Maria de Campos-Carli Antônio Lucio Teixeira Daniel Vitor Vasconcelos-Santos |
| author_facet | Jacqueline Souza Dutra Arruda Jacqueline Domingues Tibúrcio Salvina Maria de Campos-Carli Antônio Lucio Teixeira Daniel Vitor Vasconcelos-Santos |
| author_sort | Jacqueline Souza Dutra Arruda |
| collection | DOAJ |
| description | ABSTRACT: Purpose: To investigate visual-related quality of life (VRQL) and prevalence and severity of depressive symptoms in Brazilian individuals with toxoplasmic retinochoroiditis (TRC). Design: Comparative observational cross-sectional study. The National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25) and Beck Depression Inventory-II (BDI-II) were applied to respectively assess VRQL and depression in individuals consecutively seen at a uveitis referral center. Clinical/demographical data were collected. Descriptive/analytic statistics were employed, with P<0.05. Results: Patients and controls were comparable concerning age, sex and socioeconomic level. VRQL scores for all subscales were significantly lower in TRC when compared with controls, particularly associated (P<0.05) with female sex, history of ≥2 prior TRC recurrences, concomitant use of systemic corticosteroids, monocular vision and blindness. Depressive symptoms were more prevalent in TRC (55/188; 29.2%) than in controls (34/182; 18.7%) (P=0.023), also being associated with lower VRQL scores (P<0.001). Seropositive and seronegative controls for toxoplasmosis had similar VRQL scores and comparable rates of depressive symptoms. Conclusion: TRC affects VRQL in Brazilian individuals, particularly women, using systemic corticosteroids, with visual impairment and presenting recurrences of TRC. One-third of patients with TRC had evidence of depression, which was also associated with lower VRQL scores. Mental health issues in subjects with TRC should not be overlooked. |
| first_indexed | 2024-12-13T16:23:26Z |
| format | Article |
| id | doaj.art-4b5f477a470f4094bda8e72300c38e89 |
| institution | Directory Open Access Journal |
| issn | 1201-9712 |
| language | English |
| last_indexed | 2024-12-13T16:23:26Z |
| publishDate | 2021-11-01 |
| publisher | Elsevier |
| record_format | Article |
| series | International Journal of Infectious Diseases |
| spelling | doaj.art-4b5f477a470f4094bda8e72300c38e892022-12-21T23:38:39ZengElsevierInternational Journal of Infectious Diseases1201-97122021-11-011126672Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic RetinochoroiditisJacqueline Souza Dutra Arruda0Jacqueline Domingues Tibúrcio1Salvina Maria de Campos-Carli2Antônio Lucio Teixeira3Daniel Vitor Vasconcelos-Santos4Department of Ophthalmology, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Programa de Pós-Graduação em Ciências Aplicadas à Cirurgia e à Oftalmologia, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, BrazilDepartament of Medicine, Universidade Federal de São João Del Rei, São João Del Rei, Minas Gerais, BrazilPrograma Pós-Graduação em Neurociências, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, BrazilPrograma Pós-Graduação em Neurociências, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Department of Psychiatry and Behavioral Sciences, McGovern Medical School, University of Texas, Houston, USADepartment of Ophthalmology, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Programa de Pós-Graduação em Ciências Aplicadas à Cirurgia e à Oftalmologia, Faculdade de Medicina da Universidade Federal de Minas Gerais, Belo Horizonte, Brazil; Correspondence to: Daniel Vitor Vasconcelos Santos, MD PhD, Av. Alfredo Balena, 190 sala 199, Belo Horizonte MG, Brazil, 30130-100. Phone/Fax: +5531 3409-9767.ABSTRACT: Purpose: To investigate visual-related quality of life (VRQL) and prevalence and severity of depressive symptoms in Brazilian individuals with toxoplasmic retinochoroiditis (TRC). Design: Comparative observational cross-sectional study. The National Eye Institute Visual Function Questionnaire-25 (NEI-VFQ-25) and Beck Depression Inventory-II (BDI-II) were applied to respectively assess VRQL and depression in individuals consecutively seen at a uveitis referral center. Clinical/demographical data were collected. Descriptive/analytic statistics were employed, with P<0.05. Results: Patients and controls were comparable concerning age, sex and socioeconomic level. VRQL scores for all subscales were significantly lower in TRC when compared with controls, particularly associated (P<0.05) with female sex, history of ≥2 prior TRC recurrences, concomitant use of systemic corticosteroids, monocular vision and blindness. Depressive symptoms were more prevalent in TRC (55/188; 29.2%) than in controls (34/182; 18.7%) (P=0.023), also being associated with lower VRQL scores (P<0.001). Seropositive and seronegative controls for toxoplasmosis had similar VRQL scores and comparable rates of depressive symptoms. Conclusion: TRC affects VRQL in Brazilian individuals, particularly women, using systemic corticosteroids, with visual impairment and presenting recurrences of TRC. One-third of patients with TRC had evidence of depression, which was also associated with lower VRQL scores. Mental health issues in subjects with TRC should not be overlooked.http://www.sciencedirect.com/science/article/pii/S1201971221006858Ocular toxoplasmosisUveitisQuality of lifeDepression |
| spellingShingle | Jacqueline Souza Dutra Arruda Jacqueline Domingues Tibúrcio Salvina Maria de Campos-Carli Antônio Lucio Teixeira Daniel Vitor Vasconcelos-Santos Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis International Journal of Infectious Diseases Ocular toxoplasmosis Uveitis Quality of life Depression |
| title | Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis |
| title_full | Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis |
| title_fullStr | Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis |
| title_full_unstemmed | Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis |
| title_short | Vision-Related Quality Of Life And Depression In Brazilian Patients With Toxoplasmic Retinochoroiditis |
| title_sort | vision related quality of life and depression in brazilian patients with toxoplasmic retinochoroiditis |
| topic | Ocular toxoplasmosis Uveitis Quality of life Depression |
| url | http://www.sciencedirect.com/science/article/pii/S1201971221006858 |
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