Linking substrate and nucleus via actin cytoskeleton in pluripotency maintenance of mouse embryonic stem cells
Pluripotency of mouse embryonic stem cells is regulated by transcription factor regulatory networks as well as mechanical stimuli sensed by the cells. It has been unclear how the mechanical strain applied to the plasma membrane is transferred to the nucleus in mouse embryonic stem cells (mESCs). We...
Main Authors: | Brit Gracy David, Hideaki Fujita, Kyota Yasuda, Kazuko Okamoto, Yulia Panina, Junya Ichinose, Osamu Sato, Masanobu Horie, Taro Ichimura, Yasushi Okada, Tomonobu M Watanabe |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2019-12-01
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Series: | Stem Cell Research |
Online Access: | http://www.sciencedirect.com/science/article/pii/S1873506119302442 |
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