Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation

Objective: The present study aims to investigate the incidence and predictors of atrial high-rate events (AHREs) in patients with permanent pacemaker implants.Methods: A total of 289 patients who were implanted with a dual-chamber pacemaker due to complete atrioventricular block or symptomatic sick...

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Main Authors: Jian Hua Chen, Guo Yao Chen, Hong Zheng, Quan He Chen, Fa Yuan Fu, Fei Long Zhang, Liang Long Chen, Wei Wei Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fcvm.2021.728885/full
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author Jian Hua Chen
Guo Yao Chen
Hong Zheng
Quan He Chen
Fa Yuan Fu
Fei Long Zhang
Liang Long Chen
Wei Wei Wang
author_facet Jian Hua Chen
Guo Yao Chen
Hong Zheng
Quan He Chen
Fa Yuan Fu
Fei Long Zhang
Liang Long Chen
Wei Wei Wang
author_sort Jian Hua Chen
collection DOAJ
description Objective: The present study aims to investigate the incidence and predictors of atrial high-rate events (AHREs) in patients with permanent pacemaker implants.Methods: A total of 289 patients who were implanted with a dual-chamber pacemaker due to complete atrioventricular block or symptomatic sick sinus syndrome (SSS) and had no previous history of atrial fibrillation were included in the present study. AHREs are defined as events with an atrial frequency of ≥175 bpm and a duration of ≥5 min. The patients were divided into two groups according to whether or not AHREs were detected during the follow-up: group A (AHRE+, n = 91) and group N (AHRE–, n = 198).Results: During the 12-month follow-up period, AHREs were detected in 91 patients (31.5%). The multivariate Cox regression analysis revealed that patient age [odds ratio [OR] = 1.041; 95% confidence interval [CI], 1.018–1.064; and P < 0.001], pacemaker implantation due to symptomatic SSS (OR = 2.225; 95% CI, 1.227–4.036; and P = 0.008), and the percentage of atrial pacing after pacemaker implantation (OR = 1.010; 95% CI, 1.002–1.017; and P = 0.016) were independent AHRE predictors.Conclusion: The AHRE detection rate in patients with pacemaker implants was 31.5%. Patient age, pacemaker implantation due to symptomatic SSS, and the percentage of atrial pacing after pacemaker implantation were independent AHRE predictors.
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spelling doaj.art-4b621707515c4773a59281cb042d78ba2022-12-21T21:46:14ZengFrontiers Media S.A.Frontiers in Cardiovascular Medicine2297-055X2021-10-01810.3389/fcvm.2021.728885728885Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker ImplantationJian Hua Chen0Guo Yao Chen1Hong Zheng2Quan He Chen3Fa Yuan Fu4Fei Long Zhang5Liang Long Chen6Wei Wei Wang7Department of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, ChinaUnion Clinic Medical College, Fujian Medical University, Fuzhou, ChinaDepartment of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, ChinaUnion Clinic Medical College, Fujian Medical University, Fuzhou, ChinaDepartment of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, ChinaDepartment of Cardiology, Fujian Provincial Institute of Coronary Disease, Fujian Heart Medical Center, Fujian Medical University Union Hospital, Fuzhou, ChinaObjective: The present study aims to investigate the incidence and predictors of atrial high-rate events (AHREs) in patients with permanent pacemaker implants.Methods: A total of 289 patients who were implanted with a dual-chamber pacemaker due to complete atrioventricular block or symptomatic sick sinus syndrome (SSS) and had no previous history of atrial fibrillation were included in the present study. AHREs are defined as events with an atrial frequency of ≥175 bpm and a duration of ≥5 min. The patients were divided into two groups according to whether or not AHREs were detected during the follow-up: group A (AHRE+, n = 91) and group N (AHRE–, n = 198).Results: During the 12-month follow-up period, AHREs were detected in 91 patients (31.5%). The multivariate Cox regression analysis revealed that patient age [odds ratio [OR] = 1.041; 95% confidence interval [CI], 1.018–1.064; and P < 0.001], pacemaker implantation due to symptomatic SSS (OR = 2.225; 95% CI, 1.227–4.036; and P = 0.008), and the percentage of atrial pacing after pacemaker implantation (OR = 1.010; 95% CI, 1.002–1.017; and P = 0.016) were independent AHRE predictors.Conclusion: The AHRE detection rate in patients with pacemaker implants was 31.5%. Patient age, pacemaker implantation due to symptomatic SSS, and the percentage of atrial pacing after pacemaker implantation were independent AHRE predictors.https://www.frontiersin.org/articles/10.3389/fcvm.2021.728885/fullatrial high-rate eventspacemakersick sinus syndromepercentage of atrial pacingcardiology
spellingShingle Jian Hua Chen
Guo Yao Chen
Hong Zheng
Quan He Chen
Fa Yuan Fu
Fei Long Zhang
Liang Long Chen
Wei Wei Wang
Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation
Frontiers in Cardiovascular Medicine
atrial high-rate events
pacemaker
sick sinus syndrome
percentage of atrial pacing
cardiology
title Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation
title_full Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation
title_fullStr Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation
title_full_unstemmed Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation
title_short Atrial High-Rate Event Incidence and Predictors in Patients With Permanent Pacemaker Implantation
title_sort atrial high rate event incidence and predictors in patients with permanent pacemaker implantation
topic atrial high-rate events
pacemaker
sick sinus syndrome
percentage of atrial pacing
cardiology
url https://www.frontiersin.org/articles/10.3389/fcvm.2021.728885/full
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