The Geobacillus pan-genome: implications for the evolution of the genus
The genus Geobacillus is comprised of a diverse group of spore-forming Gram-positive thermophilic bacterial species and is well known for both its ecological diversity and as a source of novel thermostable enzymes. Although the mechanisms underlying the thermophilicity of the organism and the thermo...
| Main Authors: | , , , , , , |
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| Format: | Article |
| Language: | English |
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Frontiers Media S.A.
2016-05-01
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| Series: | Frontiers in Microbiology |
| Subjects: | |
| Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00723/full |
| _version_ | 1819084906373840896 |
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| author | Oliver Keoagile Ignatius Bezuidt Rian ePierneef Amine eGomri Fiyin eAdesioye Thulani Peter Makhalanyane Karima eKharroub Don A Cowan |
| author_facet | Oliver Keoagile Ignatius Bezuidt Rian ePierneef Amine eGomri Fiyin eAdesioye Thulani Peter Makhalanyane Karima eKharroub Don A Cowan |
| author_sort | Oliver Keoagile Ignatius Bezuidt |
| collection | DOAJ |
| description | The genus Geobacillus is comprised of a diverse group of spore-forming Gram-positive thermophilic bacterial species and is well known for both its ecological diversity and as a source of novel thermostable enzymes. Although the mechanisms underlying the thermophilicity of the organism and the thermostability of its macromolecules are reasonably well understood, relatively little is known of the evolutionary mechanisms, which underlie the structural and functional properties of members of this genus. In this study, we have compared 29 Geobacillus genomes, with a specific focus on the elements, which comprise the conserved core and flexible genomes. Based on comparisons of conserved core and flexible genomes, we present evidence of habitat delineation with specific Geobacillus genomes linked to specific niches. Interestingly, our analysis has shown that horizontal gene transfer is a major factor deriving the evolution of Geobacillus from Bacillus, with genetic contributions from other phylogenetically distant taxa. |
| first_indexed | 2024-12-21T20:55:54Z |
| format | Article |
| id | doaj.art-4b656befec8b41acade7d139e811d656 |
| institution | Directory Open Access Journal |
| issn | 1664-302X |
| language | English |
| last_indexed | 2024-12-21T20:55:54Z |
| publishDate | 2016-05-01 |
| publisher | Frontiers Media S.A. |
| record_format | Article |
| series | Frontiers in Microbiology |
| spelling | doaj.art-4b656befec8b41acade7d139e811d6562022-12-21T18:50:34ZengFrontiers Media S.A.Frontiers in Microbiology1664-302X2016-05-01710.3389/fmicb.2016.00723197964The Geobacillus pan-genome: implications for the evolution of the genusOliver Keoagile Ignatius Bezuidt0Rian ePierneef1Amine eGomri2Fiyin eAdesioye3Thulani Peter Makhalanyane4Karima eKharroub5Don A Cowan6University of PretoriaUniversity of PretoriaUniversité Frères Mentouri ConstantineUniversity of PretoriaUniversity of PretoriaUniversité Frères Mentouri ConstantineUniversity of PretoriaThe genus Geobacillus is comprised of a diverse group of spore-forming Gram-positive thermophilic bacterial species and is well known for both its ecological diversity and as a source of novel thermostable enzymes. Although the mechanisms underlying the thermophilicity of the organism and the thermostability of its macromolecules are reasonably well understood, relatively little is known of the evolutionary mechanisms, which underlie the structural and functional properties of members of this genus. In this study, we have compared 29 Geobacillus genomes, with a specific focus on the elements, which comprise the conserved core and flexible genomes. Based on comparisons of conserved core and flexible genomes, we present evidence of habitat delineation with specific Geobacillus genomes linked to specific niches. Interestingly, our analysis has shown that horizontal gene transfer is a major factor deriving the evolution of Geobacillus from Bacillus, with genetic contributions from other phylogenetically distant taxa.http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00723/fullGeobacillushorizontal gene transferpan-genomeSoft coreConserved coreflexible genomes |
| spellingShingle | Oliver Keoagile Ignatius Bezuidt Rian ePierneef Amine eGomri Fiyin eAdesioye Thulani Peter Makhalanyane Karima eKharroub Don A Cowan The Geobacillus pan-genome: implications for the evolution of the genus Frontiers in Microbiology Geobacillus horizontal gene transfer pan-genome Soft core Conserved core flexible genomes |
| title | The Geobacillus pan-genome: implications for the evolution of the genus |
| title_full | The Geobacillus pan-genome: implications for the evolution of the genus |
| title_fullStr | The Geobacillus pan-genome: implications for the evolution of the genus |
| title_full_unstemmed | The Geobacillus pan-genome: implications for the evolution of the genus |
| title_short | The Geobacillus pan-genome: implications for the evolution of the genus |
| title_sort | geobacillus pan genome implications for the evolution of the genus |
| topic | Geobacillus horizontal gene transfer pan-genome Soft core Conserved core flexible genomes |
| url | http://journal.frontiersin.org/Journal/10.3389/fmicb.2016.00723/full |
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