Rifampicin-induced acute thrombocytopenia
Rifampicin is an essential component of the treatment regimen for tuberculosis. Extensive clinical experience has shown that the drug is well tolerated, but on rare occasions it can cause life threatening adverse reactions like acute renal failure and thrombocytopenia. At the Tuberculosis Research C...
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Format: | Article |
Language: | English |
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Wolters Kluwer Medknow Publications
2005-01-01
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Series: | Lung India |
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Online Access: | http://www.lungindia.com/article.asp?issn=0970-2113;year=2005;volume=22;issue=4;spage=122;epage=124;aulast=Banu |
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author | Banu Rekha V Adhilakshmi A Jawahar M |
author_facet | Banu Rekha V Adhilakshmi A Jawahar M |
author_sort | Banu Rekha V |
collection | DOAJ |
description | Rifampicin is an essential component of the treatment regimen for tuberculosis. Extensive clinical experience has shown that the drug is well tolerated, but on rare occasions it can cause life threatening adverse reactions like acute renal failure and thrombocytopenia. At the Tuberculosis Research Centre, we have treated more than 8000 patients with pulmonary and extra-pulmonary tuberculosis with rifampicin-containing regimens over the past 30 years and we are reporting a case of acute thrombocytopenia probably rifampicin induced, in a patient who was retreated for tuberculosis. The physician treating tuberculosis patients must be aware of this rare life threatening complication, which if detected early, is completely reversible. |
first_indexed | 2024-12-21T18:31:24Z |
format | Article |
id | doaj.art-4b693fc507614cd2891141e6e4211a02 |
institution | Directory Open Access Journal |
issn | 0970-2113 0974-598X |
language | English |
last_indexed | 2024-12-21T18:31:24Z |
publishDate | 2005-01-01 |
publisher | Wolters Kluwer Medknow Publications |
record_format | Article |
series | Lung India |
spelling | doaj.art-4b693fc507614cd2891141e6e4211a022022-12-21T18:54:15ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2005-01-01224122124Rifampicin-induced acute thrombocytopeniaBanu Rekha VAdhilakshmi AJawahar MRifampicin is an essential component of the treatment regimen for tuberculosis. Extensive clinical experience has shown that the drug is well tolerated, but on rare occasions it can cause life threatening adverse reactions like acute renal failure and thrombocytopenia. At the Tuberculosis Research Centre, we have treated more than 8000 patients with pulmonary and extra-pulmonary tuberculosis with rifampicin-containing regimens over the past 30 years and we are reporting a case of acute thrombocytopenia probably rifampicin induced, in a patient who was retreated for tuberculosis. The physician treating tuberculosis patients must be aware of this rare life threatening complication, which if detected early, is completely reversible.http://www.lungindia.com/article.asp?issn=0970-2113;year=2005;volume=22;issue=4;spage=122;epage=124;aulast=BanuTuberculosisTreatmentRifampicinThrombocytopenia |
spellingShingle | Banu Rekha V Adhilakshmi A Jawahar M Rifampicin-induced acute thrombocytopenia Lung India Tuberculosis Treatment Rifampicin Thrombocytopenia |
title | Rifampicin-induced acute thrombocytopenia |
title_full | Rifampicin-induced acute thrombocytopenia |
title_fullStr | Rifampicin-induced acute thrombocytopenia |
title_full_unstemmed | Rifampicin-induced acute thrombocytopenia |
title_short | Rifampicin-induced acute thrombocytopenia |
title_sort | rifampicin induced acute thrombocytopenia |
topic | Tuberculosis Treatment Rifampicin Thrombocytopenia |
url | http://www.lungindia.com/article.asp?issn=0970-2113;year=2005;volume=22;issue=4;spage=122;epage=124;aulast=Banu |
work_keys_str_mv | AT banurekhav rifampicininducedacutethrombocytopenia AT adhilakshmia rifampicininducedacutethrombocytopenia AT jawaharm rifampicininducedacutethrombocytopenia |