Rifampicin-induced acute thrombocytopenia

Rifampicin is an essential component of the treatment regimen for tuberculosis. Extensive clinical experience has shown that the drug is well tolerated, but on rare occasions it can cause life threatening adverse reactions like acute renal failure and thrombocytopenia. At the Tuberculosis Research C...

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Main Authors: Banu Rekha V, Adhilakshmi A, Jawahar M
Format: Article
Language:English
Published: Wolters Kluwer Medknow Publications 2005-01-01
Series:Lung India
Subjects:
Online Access:http://www.lungindia.com/article.asp?issn=0970-2113;year=2005;volume=22;issue=4;spage=122;epage=124;aulast=Banu
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author Banu Rekha V
Adhilakshmi A
Jawahar M
author_facet Banu Rekha V
Adhilakshmi A
Jawahar M
author_sort Banu Rekha V
collection DOAJ
description Rifampicin is an essential component of the treatment regimen for tuberculosis. Extensive clinical experience has shown that the drug is well tolerated, but on rare occasions it can cause life threatening adverse reactions like acute renal failure and thrombocytopenia. At the Tuberculosis Research Centre, we have treated more than 8000 patients with pulmonary and extra-pulmonary tuberculosis with rifampicin-containing regimens over the past 30 years and we are reporting a case of acute thrombocytopenia probably rifampicin induced, in a patient who was retreated for tuberculosis. The physician treating tuberculosis patients must be aware of this rare life threatening complication, which if detected early, is completely reversible.
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spelling doaj.art-4b693fc507614cd2891141e6e4211a022022-12-21T18:54:15ZengWolters Kluwer Medknow PublicationsLung India0970-21130974-598X2005-01-01224122124Rifampicin-induced acute thrombocytopeniaBanu Rekha VAdhilakshmi AJawahar MRifampicin is an essential component of the treatment regimen for tuberculosis. Extensive clinical experience has shown that the drug is well tolerated, but on rare occasions it can cause life threatening adverse reactions like acute renal failure and thrombocytopenia. At the Tuberculosis Research Centre, we have treated more than 8000 patients with pulmonary and extra-pulmonary tuberculosis with rifampicin-containing regimens over the past 30 years and we are reporting a case of acute thrombocytopenia probably rifampicin induced, in a patient who was retreated for tuberculosis. The physician treating tuberculosis patients must be aware of this rare life threatening complication, which if detected early, is completely reversible.http://www.lungindia.com/article.asp?issn=0970-2113;year=2005;volume=22;issue=4;spage=122;epage=124;aulast=BanuTuberculosisTreatmentRifampicinThrombocytopenia
spellingShingle Banu Rekha V
Adhilakshmi A
Jawahar M
Rifampicin-induced acute thrombocytopenia
Lung India
Tuberculosis
Treatment
Rifampicin
Thrombocytopenia
title Rifampicin-induced acute thrombocytopenia
title_full Rifampicin-induced acute thrombocytopenia
title_fullStr Rifampicin-induced acute thrombocytopenia
title_full_unstemmed Rifampicin-induced acute thrombocytopenia
title_short Rifampicin-induced acute thrombocytopenia
title_sort rifampicin induced acute thrombocytopenia
topic Tuberculosis
Treatment
Rifampicin
Thrombocytopenia
url http://www.lungindia.com/article.asp?issn=0970-2113;year=2005;volume=22;issue=4;spage=122;epage=124;aulast=Banu
work_keys_str_mv AT banurekhav rifampicininducedacutethrombocytopenia
AT adhilakshmia rifampicininducedacutethrombocytopenia
AT jawaharm rifampicininducedacutethrombocytopenia