A Prism Vote method for individualized risk prediction of traits in genotype data of Multi-population.
Multi-population cohorts offer unprecedented opportunities for profiling disease risk in large samples, however, heterogeneous risk effects underlying complex traits across populations make integrative prediction challenging. In this study, we propose a novel Bayesian probability framework, the Pris...
Main Authors: | Xiaoxuan Xia, Yexian Zhang, Rui Sun, Yingying Wei, Qi Li, Marc Ka Chun Chong, William Ka Kei Wu, Benny Chung-Ying Zee, Hua Tang, Maggie Haitian Wang |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2022-10-01
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Series: | PLoS Genetics |
Online Access: | https://doi.org/10.1371/journal.pgen.1010443 |
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