Single-cell sequencing reveals homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-induced AKI

Abstract Homogeneity and heterogeneity of the cytopathological mechanisms in different etiology-induced acute kidney injury (AKI) are poorly understood. Here, we performed single-cell sequencing (scRNA) on mouse kidneys with five common AKI etiologies (CP-Cisplatin, IRI-Ischemia-reperfusion injury,...

Full description

Bibliographic Details
Main Authors: Zhimin Chen, Yinshuang Li, Ying Yuan, Kunmei Lai, Keng Ye, Yujiao Lin, Ruilong Lan, Hong Chen, Yanfang Xu
Format: Article
Language:English
Published: Nature Publishing Group 2023-05-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-05830-z