The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments
The vaginal microbiota plays a critical role in the health of the female genital tract, and its composition contributes to gynecological disorders and infertility. Lactobacilli are the dominant species in the female genital tract: their production of lactic acid, hydrogen peroxide, and bacteriocins...
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| Format: | Article |
| Language: | English |
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MDPI AG
2023-05-01
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| Series: | Microorganisms |
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| Online Access: | https://www.mdpi.com/2076-2607/11/6/1443 |
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| author | Giovanna Cocomazzi Silvia De Stefani Lino Del Pup Simone Palini Matteo Buccheri Mariangela Primiterra Natale Sciannamè Raffaele Faioli Annamaria Maglione Giorgio Maria Baldini Domenico Baldini Valerio Pazienza |
| author_facet | Giovanna Cocomazzi Silvia De Stefani Lino Del Pup Simone Palini Matteo Buccheri Mariangela Primiterra Natale Sciannamè Raffaele Faioli Annamaria Maglione Giorgio Maria Baldini Domenico Baldini Valerio Pazienza |
| author_sort | Giovanna Cocomazzi |
| collection | DOAJ |
| description | The vaginal microbiota plays a critical role in the health of the female genital tract, and its composition contributes to gynecological disorders and infertility. Lactobacilli are the dominant species in the female genital tract: their production of lactic acid, hydrogen peroxide, and bacteriocins prevents the invasion and growth of pathogenic microorganisms. Several factors such as hormonal changes, age of reproduction, sexual practices, menstrual cycle, pregnancy, and antimicrobial drugs use can cause imbalance and dysbiosis of the vaginal microbiota. This review aims to highlight the impact of the vaginal microbiota in Assisted Reproductive Technology techniques (ART) and it examines the factors that influence the vaginal microbiota, the consequences of dysbiosis, and potential interventions to restore a healthy female genital tract. |
| first_indexed | 2024-03-11T02:08:10Z |
| format | Article |
| id | doaj.art-4b6c4c4c031d4d71a4b4a2ab5a7df389 |
| institution | Directory Open Access Journal |
| issn | 2076-2607 |
| language | English |
| last_indexed | 2024-03-11T02:08:10Z |
| publishDate | 2023-05-01 |
| publisher | MDPI AG |
| record_format | Article |
| series | Microorganisms |
| spelling | doaj.art-4b6c4c4c031d4d71a4b4a2ab5a7df3892023-11-18T11:41:58ZengMDPI AGMicroorganisms2076-26072023-05-01116144310.3390/microorganisms11061443The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction TreatmentsGiovanna Cocomazzi0Silvia De Stefani1Lino Del Pup2Simone Palini3Matteo Buccheri4Mariangela Primiterra5Natale Sciannamè6Raffaele Faioli7Annamaria Maglione8Giorgio Maria Baldini9Domenico Baldini10Valerio Pazienza11Division of Gastroenterology, Fondazione IRCCS-Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, ItalyClinica Nuova Ricerca, Via Settembrini 17/h, 47923 Rimini, ItalyGynecological Endocrinology and Fertility, University Sanitary Agency Friuli Central (ASUFC), Via Pozzuolo, 330, 33100 Udine, ItalyOspedale “Cervesi” di Cattolica—AUSL Romagna Via Ludwig Van Beethoven, 1, 47841 Cattolica, ItalyInstituto Bernabeu Via Castellana, 88, 30030 Martellago, ItalyClinica Nuova Ricerca, Via Settembrini 17/h, 47923 Rimini, ItalyGynecology and Obstetrics, IRCCS “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyGynecology and Obstetrics, IRCCS “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyGynecology and Obstetrics, IRCCS “Casa Sollievo della Sofferenza”, 71013 San Giovanni Rotondo, ItalyIVF Center, Momò Fertilife, 76011 Bisceglie Via Cala dell’Arciprete, 76011 Bisceglie, ItalyIVF Center, Momò Fertilife, 76011 Bisceglie Via Cala dell’Arciprete, 76011 Bisceglie, ItalyDivision of Gastroenterology, Fondazione IRCCS-Casa Sollievo della Sofferenza, 71013 San Giovanni Rotondo, ItalyThe vaginal microbiota plays a critical role in the health of the female genital tract, and its composition contributes to gynecological disorders and infertility. Lactobacilli are the dominant species in the female genital tract: their production of lactic acid, hydrogen peroxide, and bacteriocins prevents the invasion and growth of pathogenic microorganisms. Several factors such as hormonal changes, age of reproduction, sexual practices, menstrual cycle, pregnancy, and antimicrobial drugs use can cause imbalance and dysbiosis of the vaginal microbiota. This review aims to highlight the impact of the vaginal microbiota in Assisted Reproductive Technology techniques (ART) and it examines the factors that influence the vaginal microbiota, the consequences of dysbiosis, and potential interventions to restore a healthy female genital tract.https://www.mdpi.com/2076-2607/11/6/1443vaginal microbiotabacterial vaginosisassisted reproduction technologiesendometriosisinfertilitypregnancy outcome |
| spellingShingle | Giovanna Cocomazzi Silvia De Stefani Lino Del Pup Simone Palini Matteo Buccheri Mariangela Primiterra Natale Sciannamè Raffaele Faioli Annamaria Maglione Giorgio Maria Baldini Domenico Baldini Valerio Pazienza The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments Microorganisms vaginal microbiota bacterial vaginosis assisted reproduction technologies endometriosis infertility pregnancy outcome |
| title | The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments |
| title_full | The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments |
| title_fullStr | The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments |
| title_full_unstemmed | The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments |
| title_short | The Impact of the Female Genital Microbiota on the Outcome of Assisted Reproduction Treatments |
| title_sort | impact of the female genital microbiota on the outcome of assisted reproduction treatments |
| topic | vaginal microbiota bacterial vaginosis assisted reproduction technologies endometriosis infertility pregnancy outcome |
| url | https://www.mdpi.com/2076-2607/11/6/1443 |
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