Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1

Mesenchymal stem cell-derived extracellular vesicles exert pro-angiogenic and pro-lymphangiogenic effects in ischemic tissues by transferring various microRNAs and proteins including ITGa5 and NRP1

Abstract Mesenchymal stem cells/stromal cells (MSCs)-derived extracellular vesicles (EVs) mediate pro-regenerative effects in damaged ischemic tissues by regulating angiogenesis. MSCs-EVs modulate functions of cells including endogenous mature cells, progenitors and stem cells, resulting in restorat...

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Bibliographic Details
Main Authors: Anna Łabędź-Masłowska, Luisa Vergori, Sylwia Kędracka-Krok, Elżbieta Karnas, Sylwia Bobis-Wozowicz, Małgorzata Sekuła-Stryjewska, Michał Sarna, Ramaroson Andriantsitohaina, Ewa K. Zuba-Surma
Format: Article
Language:English
Published: BMC 2024-02-01
Series:Journal of Nanobiotechnology
Subjects:
Extracellular vesicles
Mesenchymal stem cells
Ischemic tissue regeneration
Angiogenesis
Lymphangiogenesis
Online Access:https://doi.org/10.1186/s12951-024-02304-y

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