Studying the Effect of Sertraline in Reducing Aggressive Behavior in Patients with Major Depression
Purpose: Depression causes dysfunction in various spheres of individual and social life, which is now considered as the fourth-leading cause of the global disease burden. Given that violence and aggression associated with depression in the community cause serious damage to the family, the prediction...
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| Format: | Article |
| Language: | English |
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Tabriz University of Medical Sciences
2017-06-01
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| Series: | Advanced Pharmaceutical Bulletin |
| Subjects: | |
| Online Access: | http://journals.tbzmed.ac.ir/APB/Manuscript/APB-7-275.pdf |
| _version_ | 1818753030609174528 |
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| author | Alireza Farnam Arezoo MehrAra Hossein Dadashzadeh Golamreza Chalabianlou Salman Safikhanlou |
| author_facet | Alireza Farnam Arezoo MehrAra Hossein Dadashzadeh Golamreza Chalabianlou Salman Safikhanlou |
| author_sort | Alireza Farnam |
| collection | DOAJ |
| description | Purpose: Depression causes dysfunction in various spheres of
individual and social life, which is now considered as the fourth-leading cause
of the global disease burden. Given that violence and aggression associated
with depression in the community cause serious damage to the family, the
prediction, early detection and effective treatment of aggressive and violent
behavior are essential. The present study compared the severity of aggression
before and after treatment with sertraline in patients with major depression.
Methods: This is an intervention type study and the study
population consisted of patients with depression and aggression. The sampling
included 23 eligible patients. Data were obtained by SCID-I, SCID-II, STAXI-II,
BDI-II and was also analyzed using SPSS 23 software.
Results: The results showed that depression, anger mood, desire
to verbally express anger, controlling anger and anger control before treatment
was reduced but the desire for physical expression of anger increased.
Conclusion: Obtained results in this research support the
effect of Sertraline on reduction of severity of depression, reduction of
severity of symptoms of aggression and anger (state of anger, anger feeling,
and the tendency to express anger verbally), increased controlling external
anger and significantly controlling internal anger. Hence, Sertraline can be
found effective in the treatment of patients with depression and aggressive
behaviors. Also Sertraline increases tend to cause physical representation of
anger, then this issue supports the increase in the euthanasia behavior in
primary days of treatment with SSRI that requires more assessments. |
| first_indexed | 2024-12-18T05:00:53Z |
| format | Article |
| id | doaj.art-4b75109f92e1464993ba93d04e3e2bd0 |
| institution | Directory Open Access Journal |
| issn | 2228-5881 2251-7308 |
| language | English |
| last_indexed | 2024-12-18T05:00:53Z |
| publishDate | 2017-06-01 |
| publisher | Tabriz University of Medical Sciences |
| record_format | Article |
| series | Advanced Pharmaceutical Bulletin |
| spelling | doaj.art-4b75109f92e1464993ba93d04e3e2bd02022-12-21T21:20:09ZengTabriz University of Medical SciencesAdvanced Pharmaceutical Bulletin2228-58812251-73082017-06-017227527910.15171/apb.2017.033APB_14580_20160825101452Studying the Effect of Sertraline in Reducing Aggressive Behavior in Patients with Major DepressionAlireza Farnam0Arezoo MehrAra1Hossein Dadashzadeh2Golamreza Chalabianlou3Salman Safikhanlou4Research Center of Psychiatry and Behavioral Sciences, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Research Center of Psychiatry and Behavioral Sciences, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Research Center of Psychiatry and Behavioral Sciences, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Research Center of Psychiatry and Behavioral Sciences, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Research Center of Psychiatry and Behavioral Sciences, Razi Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.Purpose: Depression causes dysfunction in various spheres of individual and social life, which is now considered as the fourth-leading cause of the global disease burden. Given that violence and aggression associated with depression in the community cause serious damage to the family, the prediction, early detection and effective treatment of aggressive and violent behavior are essential. The present study compared the severity of aggression before and after treatment with sertraline in patients with major depression. Methods: This is an intervention type study and the study population consisted of patients with depression and aggression. The sampling included 23 eligible patients. Data were obtained by SCID-I, SCID-II, STAXI-II, BDI-II and was also analyzed using SPSS 23 software. Results: The results showed that depression, anger mood, desire to verbally express anger, controlling anger and anger control before treatment was reduced but the desire for physical expression of anger increased. Conclusion: Obtained results in this research support the effect of Sertraline on reduction of severity of depression, reduction of severity of symptoms of aggression and anger (state of anger, anger feeling, and the tendency to express anger verbally), increased controlling external anger and significantly controlling internal anger. Hence, Sertraline can be found effective in the treatment of patients with depression and aggressive behaviors. Also Sertraline increases tend to cause physical representation of anger, then this issue supports the increase in the euthanasia behavior in primary days of treatment with SSRI that requires more assessments.http://journals.tbzmed.ac.ir/APB/Manuscript/APB-7-275.pdfDepressionAggressionSertralineSTAXI-II |
| spellingShingle | Alireza Farnam Arezoo MehrAra Hossein Dadashzadeh Golamreza Chalabianlou Salman Safikhanlou Studying the Effect of Sertraline in Reducing Aggressive Behavior in Patients with Major Depression Advanced Pharmaceutical Bulletin Depression Aggression Sertraline STAXI-II |
| title | Studying the Effect of Sertraline in Reducing Aggressive Behavior in
Patients with Major Depression |
| title_full | Studying the Effect of Sertraline in Reducing Aggressive Behavior in
Patients with Major Depression |
| title_fullStr | Studying the Effect of Sertraline in Reducing Aggressive Behavior in
Patients with Major Depression |
| title_full_unstemmed | Studying the Effect of Sertraline in Reducing Aggressive Behavior in
Patients with Major Depression |
| title_short | Studying the Effect of Sertraline in Reducing Aggressive Behavior in
Patients with Major Depression |
| title_sort | studying the effect of sertraline in reducing aggressive behavior in patients with major depression |
| topic | Depression Aggression Sertraline STAXI-II |
| url | http://journals.tbzmed.ac.ir/APB/Manuscript/APB-7-275.pdf |
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