The impact of blood transcriptomic biomarker targeted tuberculosis preventive therapy in people living with HIV: a mathematical modelling study

The impact of blood transcriptomic biomarker targeted tuberculosis preventive therapy in people living with HIV: a mathematical modelling study

Abstract Background Tuberculosis (TB) preventive therapy is recommended for all people living with HIV (PLHIV). Despite the elevated risk of TB amongst PLHIV, most of those eligible for preventive therapy would never develop TB. Tests which can identify individuals at greatest risk of disease would...

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Bibliographic Details
Main Authors: Tom Sumner, Simon C. Mendelsohn, Thomas J. Scriba, Mark Hatherill, Richard G. White
Format: Article
Language:English
Published: BMC 2021-10-01
Series:BMC Medicine
Subjects:
Tuberculosis
HIV
Preventive therapy
Biomarker
Modelling
Online Access:https://doi.org/10.1186/s12916-021-02127-w

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