Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature
This paper reports a rare case of Low-grade fibromyxoid sarcoma (LGFMS) that occurred primarily in the parapharyngeal space, in a 57-year-old woman. To the best of our knowledge, this is the first case of LGFMS arising from the parapharingeal space reported in the literature. Primary sarcomas of the...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
2020-06-01
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| Series: | Oral and Maxillofacial Surgery Cases |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S2214541920300134 |
| _version_ | 1819007248305750016 |
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| author | Corrado Toro Paola Costa Giada Maria Vecchio Gaetano Magro |
| author_facet | Corrado Toro Paola Costa Giada Maria Vecchio Gaetano Magro |
| author_sort | Corrado Toro |
| collection | DOAJ |
| description | This paper reports a rare case of Low-grade fibromyxoid sarcoma (LGFMS) that occurred primarily in the parapharyngeal space, in a 57-year-old woman. To the best of our knowledge, this is the first case of LGFMS arising from the parapharingeal space reported in the literature. Primary sarcomas of the head and neck region are very rare, accounting for approximately 1% of malignancies in this region. LGFMS is a distinctive type of soft-tissue sarcoma that was first described by Evans in 1987. LGFMS may be included in the differential diagnosis of tumors of the parapharyngeal space, and especially among the bland-looking spindle cell lesions. Despite its bland-looking morphology, this sarcoma should be recognized to avoid confusion with other bland-looking benign spindle cell lesions. Radical surgical resection with clear margins, is the treatment of choice of LGFMS. Despite its bland-looking histologic appearance, it is characterized by a malignant behavior with high rates of local recurrence and metastatic spread. For these reasones, all patients with LGFMS are recommended for long-term follow-up. |
| first_indexed | 2024-12-21T00:21:34Z |
| format | Article |
| id | doaj.art-4b76f0e1e80f4d20b19ccd8f9403bf09 |
| institution | Directory Open Access Journal |
| issn | 2214-5419 |
| language | English |
| last_indexed | 2024-12-21T00:21:34Z |
| publishDate | 2020-06-01 |
| publisher | Elsevier |
| record_format | Article |
| series | Oral and Maxillofacial Surgery Cases |
| spelling | doaj.art-4b76f0e1e80f4d20b19ccd8f9403bf092022-12-21T19:22:06ZengElsevierOral and Maxillofacial Surgery Cases2214-54192020-06-0162Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literatureCorrado Toro0Paola Costa1Giada Maria Vecchio2Gaetano Magro3Maxillofacial Surgery Unit (Head C. Toro), Clinica del Mediterraneo Private Hospital, Ragusa, Italy; Corresponding author. Head of Maxillofacial Surgery Unit, ''Clinica del Mediterraneo'' Hospital, Viale E. Fieramosca 100, 97100, Ragusa, Italy.DMD Private Practice, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies, G.F. Ingrassia, Anatomic Pathology Section (Head G. Magro), University of Catania, Catania, ItalyDepartment of Medical and Surgical Sciences and Advanced Technologies, G.F. Ingrassia, Anatomic Pathology Section (Head G. Magro), University of Catania, Catania, ItalyThis paper reports a rare case of Low-grade fibromyxoid sarcoma (LGFMS) that occurred primarily in the parapharyngeal space, in a 57-year-old woman. To the best of our knowledge, this is the first case of LGFMS arising from the parapharingeal space reported in the literature. Primary sarcomas of the head and neck region are very rare, accounting for approximately 1% of malignancies in this region. LGFMS is a distinctive type of soft-tissue sarcoma that was first described by Evans in 1987. LGFMS may be included in the differential diagnosis of tumors of the parapharyngeal space, and especially among the bland-looking spindle cell lesions. Despite its bland-looking morphology, this sarcoma should be recognized to avoid confusion with other bland-looking benign spindle cell lesions. Radical surgical resection with clear margins, is the treatment of choice of LGFMS. Despite its bland-looking histologic appearance, it is characterized by a malignant behavior with high rates of local recurrence and metastatic spread. For these reasones, all patients with LGFMS are recommended for long-term follow-up.http://www.sciencedirect.com/science/article/pii/S2214541920300134 |
| spellingShingle | Corrado Toro Paola Costa Giada Maria Vecchio Gaetano Magro Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature Oral and Maxillofacial Surgery Cases |
| title | Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature |
| title_full | Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature |
| title_fullStr | Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature |
| title_full_unstemmed | Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature |
| title_short | Low-grade fibromyxoid sarcoma of the parapharyngeal space: A case report and review of the literature |
| title_sort | low grade fibromyxoid sarcoma of the parapharyngeal space a case report and review of the literature |
| url | http://www.sciencedirect.com/science/article/pii/S2214541920300134 |
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