Motility Dynamics of T Cells in Tumor-Draining Lymph Nodes: A Rational Indicator of Antitumor Response and Immune Checkpoint Blockade

The migration status of T cells within the densely packed tissue environment of lymph nodes reflects the ongoing activation state of adaptive immune responses. Upon encountering antigen-presenting dendritic cells, actively migrating T cells that are specific to cognate antigens slow down and are eve...

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Bibliographic Details
Main Authors: Yasuhiro Kanda, Taku Okazaki, Tomoya Katakai
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/13/18/4616