Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data

Recent studies have established the potential of classifiers designed using association rule mining methods. The current study proposes such an associative classifier to efficiently detect dengue fever using gene expression data. Labelled gene expression data has been preprocessed and discretized to...

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Main Authors: Diptaraj Sen, Saubhik Paladhi, Jaroslav Frnda, Sankhadeep Chatterjee, Soumen Banerjee, Jan Nedoma
Format: Article
Language:English
Published: IEEE 2022-01-01
Series:IEEE Access
Subjects:
Online Access:https://ieeexplore.ieee.org/document/9857884/
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author Diptaraj Sen
Saubhik Paladhi
Jaroslav Frnda
Sankhadeep Chatterjee
Soumen Banerjee
Jan Nedoma
author_facet Diptaraj Sen
Saubhik Paladhi
Jaroslav Frnda
Sankhadeep Chatterjee
Soumen Banerjee
Jan Nedoma
author_sort Diptaraj Sen
collection DOAJ
description Recent studies have established the potential of classifiers designed using association rule mining methods. The current study proposes such an associative classifier to efficiently detect dengue fever using gene expression data. Labelled gene expression data has been preprocessed and discretized to mine association rules using well-established rule mining methods. Thereafter, unsupervised clustering methods have been applied to the discretized gene expression data to reduce and select the most promising features. The final feature reduced discretized gene expression data is subsequently used to mine rules in order to classify subjects into ‘Dengue Fever’ or ‘Healthy’. Two well-known association rule mining methods, viz., Apriori and FP-Growth, have been used here along with various types of well established clustering methods. Extensive analysis has been reported with performance parameters in terms of accuracy, precision, recall and false positive rate using 5-fold cross-validation. Furthermore, a separate investigation has been conducted to find the most suitable number of features and confidence of association rule mining methods. The experimental results obtained indicate accurate detection of dengue fever patients at an early stage using the proposed associative classification method.
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spelling doaj.art-4b817b5e57174e6193cd8c57b189b66d2022-12-22T03:07:42ZengIEEEIEEE Access2169-35362022-01-0110883408835310.1109/ACCESS.2022.31989379857884Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression DataDiptaraj Sen0Saubhik Paladhi1Jaroslav Frnda2https://orcid.org/0000-0001-6065-3087Sankhadeep Chatterjee3https://orcid.org/0000-0002-3930-4699Soumen Banerjee4https://orcid.org/0000-0003-3918-1892Jan Nedoma5https://orcid.org/0000-0001-7459-2043Department of Computer Science and Engineering, University of Engineering and Management, Kolkata, IndiaDepartment of Computer Science and Engineering, University of Kalyani, Kalyani, IndiaDepartment of Telecommunications, VSB—Technical University of Ostrava, Ostrava, Czech RepublicDepartment of Computer Science and Technology, University of Engineering and Management, Kolkata, IndiaDepartment of Electronics and Communication Engineering, University of Engineering and Management, Kolkata, IndiaDepartment of Telecommunications, VSB—Technical University of Ostrava, Ostrava, Czech RepublicRecent studies have established the potential of classifiers designed using association rule mining methods. The current study proposes such an associative classifier to efficiently detect dengue fever using gene expression data. Labelled gene expression data has been preprocessed and discretized to mine association rules using well-established rule mining methods. Thereafter, unsupervised clustering methods have been applied to the discretized gene expression data to reduce and select the most promising features. The final feature reduced discretized gene expression data is subsequently used to mine rules in order to classify subjects into ‘Dengue Fever’ or ‘Healthy’. Two well-known association rule mining methods, viz., Apriori and FP-Growth, have been used here along with various types of well established clustering methods. Extensive analysis has been reported with performance parameters in terms of accuracy, precision, recall and false positive rate using 5-fold cross-validation. Furthermore, a separate investigation has been conducted to find the most suitable number of features and confidence of association rule mining methods. The experimental results obtained indicate accurate detection of dengue fever patients at an early stage using the proposed associative classification method.https://ieeexplore.ieee.org/document/9857884/Gene expression dataassociation rulesApriori algorithmFP-growth algorithmclustering
spellingShingle Diptaraj Sen
Saubhik Paladhi
Jaroslav Frnda
Sankhadeep Chatterjee
Soumen Banerjee
Jan Nedoma
Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data
IEEE Access
Gene expression data
association rules
Apriori algorithm
FP-growth algorithm
clustering
title Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data
title_full Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data
title_fullStr Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data
title_full_unstemmed Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data
title_short Associative Classifier Coupled With Unsupervised Feature Reduction for Dengue Fever Classification Using Gene Expression Data
title_sort associative classifier coupled with unsupervised feature reduction for dengue fever classification using gene expression data
topic Gene expression data
association rules
Apriori algorithm
FP-growth algorithm
clustering
url https://ieeexplore.ieee.org/document/9857884/
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AT saubhikpaladhi associativeclassifiercoupledwithunsupervisedfeaturereductionfordenguefeverclassificationusinggeneexpressiondata
AT jaroslavfrnda associativeclassifiercoupledwithunsupervisedfeaturereductionfordenguefeverclassificationusinggeneexpressiondata
AT sankhadeepchatterjee associativeclassifiercoupledwithunsupervisedfeaturereductionfordenguefeverclassificationusinggeneexpressiondata
AT soumenbanerjee associativeclassifiercoupledwithunsupervisedfeaturereductionfordenguefeverclassificationusinggeneexpressiondata
AT jannedoma associativeclassifiercoupledwithunsupervisedfeaturereductionfordenguefeverclassificationusinggeneexpressiondata