Immortalized erythroid cells as a novel frontier for in vitro blood production: current approaches and potential clinical application

Immortalized erythroid cells as a novel frontier for in vitro blood production: current approaches and potential clinical application

Abstract Background Blood transfusions represent common medical procedures, which provide essential supportive therapy. However, these procedures are notoriously expensive for healthcare services and not without risk. The potential threat of transfusion-related complications, such as the development...

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Bibliographic Details
Main Authors: Christian Felice Cervellera, Chiara Mazziotta, Giulia Di Mauro, Maria Rosa Iaquinta, Elisa Mazzoni, Elena Torreggiani, Mauro Tognon, Fernanda Martini, John Charles Rotondo
Format: Article
Language:English
Published: BMC 2023-05-01
Series:Stem Cell Research & Therapy
Subjects:
Erythroblasts
Immortalization
Hematopoietic stem cells
Erythropoiesis
Cell differentiation
Genetic engineering
Online Access:https://doi.org/10.1186/s13287-023-03367-8

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