Topical administration of the secretome derived from human amniotic epithelial cells ameliorates psoriasis-like skin lesions in mice

Topical administration of the secretome derived from human amniotic epithelial cells ameliorates psoriasis-like skin lesions in mice

Abstract Background Psoriasis is a chronic inflammatory skin disease. Tissue stem cells have exhibited a therapeutic effect on psoriatic mice. However, the therapeutic effect of topical administration of the secretome derived from tissue stem cells on psoriasis has not been reported. Methods The sec...

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Bibliographic Details
Main Authors: Mengbo Yang, Lanqi Wang, Zhimin Chen, Weijie Hao, Qian You, Jianhua Lin, Jingzhi Tang, Xin Zhao, Wei-Qiang Gao, Huiming Xu
Format: Article
Language:English
Published: BMC 2022-08-01
Series:Stem Cell Research & Therapy
Subjects:
Psoriasis
AEC-SC
Skin lesions
Skin inflammation
IL-1ra
Online Access:https://doi.org/10.1186/s13287-022-03091-9

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