Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma
The aim of the study was to study the role of allogeneic transplantation of hematopoietic stem cells in a patient with the classic course of Hodgkin's lymphoma.Materials and methods. The work was carried out on the basis of the analysis of a clinical case of the clinic of occupational pathology...
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| Format: | Article |
| Language: | Russian |
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Private institution educational organization of higher education "Medical University "ReaViz"
2021-05-01
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| Series: | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
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| Online Access: | https://vestnik.reaviz.ru/jour/article/view/217 |
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| author | A. Р. Strelnikova E. V. Sarksyan V. S. Bogova A. N. Levanov Т. V. Shelekhova N. I. Lviv |
| author_facet | A. Р. Strelnikova E. V. Sarksyan V. S. Bogova A. N. Levanov Т. V. Shelekhova N. I. Lviv |
| author_sort | A. Р. Strelnikova |
| collection | DOAJ |
| description | The aim of the study was to study the role of allogeneic transplantation of hematopoietic stem cells in a patient with the classic course of Hodgkin's lymphoma.Materials and methods. The work was carried out on the basis of the analysis of a clinical case of the clinic of occupational pathology and hematology of the University Clinical Hospital No. Professor V.Ya. Shustov. Examinations, a course of chemotherapy in conjunction with surgery and analysis of the results of a patient with a diagnosis of classic Hodgkin's lymphoma were carried out. Results. An unfavorable prognostic effect of a large amount of previous chemotherapy on overall survival after allogeneic HSC transplantation was revealed. According to the results of PET-CT, the patient achieved PETnegative remission of the disease after all the stages of treatment. Compared to the presented PET / CT scan of 02/07/2020, there is a positive trend in the form of the disappearance of metabolic activity in the 3rd rib on the right, the body of Th 11 and the body of the left ilium.Conclusion. The use of high-dose chemotherapy with hematopoietic stem cell transplantation makes it possible to achieve success in the treatment of patients in cases where the results of chemotherapy are unsatisfactory. |
| first_indexed | 2024-03-12T03:45:26Z |
| format | Article |
| id | doaj.art-4b833bea1299414b824a6ee1fb99ae31 |
| institution | Directory Open Access Journal |
| issn | 2226-762X 2782-1579 |
| language | Russian |
| last_indexed | 2024-03-12T03:45:26Z |
| publishDate | 2021-05-01 |
| publisher | Private institution educational organization of higher education "Medical University "ReaViz" |
| record_format | Article |
| series | Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье |
| spelling | doaj.art-4b833bea1299414b824a6ee1fb99ae312023-09-03T12:58:04ZrusPrivate institution educational organization of higher education "Medical University "ReaViz"Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье2226-762X2782-15792021-05-010211312110.20340/vmi-rvz.2021.2.TX.1177Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphomaA. Р. Strelnikova0E. V. Sarksyan1V. S. Bogova2A. N. Levanov3Т. V. Shelekhova4N. I. Lviv5Саратовский государственный медицинский университет имени В.И. РазумовскогоСаратовский государственный медицинский университет имени В.И. РазумовскогоСаратовский государственный медицинский университет имени В.И. РазумовскогоСаратовский государственный медицинский университет имени В.И. РазумовскогоСаратовский государственный медицинский университет имени В.И. РазумовскогоСаратовский государственный медицинский университет имени В.И. РазумовскогоThe aim of the study was to study the role of allogeneic transplantation of hematopoietic stem cells in a patient with the classic course of Hodgkin's lymphoma.Materials and methods. The work was carried out on the basis of the analysis of a clinical case of the clinic of occupational pathology and hematology of the University Clinical Hospital No. Professor V.Ya. Shustov. Examinations, a course of chemotherapy in conjunction with surgery and analysis of the results of a patient with a diagnosis of classic Hodgkin's lymphoma were carried out. Results. An unfavorable prognostic effect of a large amount of previous chemotherapy on overall survival after allogeneic HSC transplantation was revealed. According to the results of PET-CT, the patient achieved PETnegative remission of the disease after all the stages of treatment. Compared to the presented PET / CT scan of 02/07/2020, there is a positive trend in the form of the disappearance of metabolic activity in the 3rd rib on the right, the body of Th 11 and the body of the left ilium.Conclusion. The use of high-dose chemotherapy with hematopoietic stem cell transplantation makes it possible to achieve success in the treatment of patients in cases where the results of chemotherapy are unsatisfactory.https://vestnik.reaviz.ru/jour/article/view/217лимфома ходжкинааллогенная трансплантация гемопоэтических стволовых клетокэффективностьосложненияродственный донор гемопоэтических стволовых клеток |
| spellingShingle | A. Р. Strelnikova E. V. Sarksyan V. S. Bogova A. N. Levanov Т. V. Shelekhova N. I. Lviv Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma Вестник медицинского института «Реавиз»: Реабилитация, врач и здоровье лимфома ходжкина аллогенная трансплантация гемопоэтических стволовых клеток эффективность осложнения родственный донор гемопоэтических стволовых клеток |
| title | Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma |
| title_full | Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma |
| title_fullStr | Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma |
| title_full_unstemmed | Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma |
| title_short | Results of allogeneic hematopoietic stem cell transplantation in a patient with classical Hodgkin's lymphoma |
| title_sort | results of allogeneic hematopoietic stem cell transplantation in a patient with classical hodgkin s lymphoma |
| topic | лимфома ходжкина аллогенная трансплантация гемопоэтических стволовых клеток эффективность осложнения родственный донор гемопоэтических стволовых клеток |
| url | https://vestnik.reaviz.ru/jour/article/view/217 |
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