Signatures of Selection at Drug Resistance Loci in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

Signatures of Selection at Drug Resistance Loci in <named-content content-type="genus-species">Mycobacterium tuberculosis</named-content>

ABSTRACT Tuberculosis (TB) is the leading cause of death by an infectious disease, and global TB control efforts are increasingly threatened by drug resistance in Mycobacterium tuberculosis. Unlike most bacteria, where lateral gene transfer is an important mechanism of resistance acquisition, resist...

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Bibliographic Details
Main Authors: Tatum D. Mortimer, Alexandra M. Weber, Caitlin S. Pepperell
Format: Article
Language:English
Published: American Society for Microbiology 2018-02-01
Series:mSystems
Subjects:
Mycobacterium tuberculosis
antibiotic resistance
evolution
genomics
positive selection
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00108-17

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