Trypanocidal activity of organotin chlorides on Trypanosoma brucei-infected mice

Trypanocidal activity of organotin chlorides on Trypanosoma brucei-infected mice

The organotin compounds dibulyltin (DBTC) and diphenyltin dichlorides (DPTC) were tested for trypanocidal activity on a Trypanosoma brucei-infected mice model. At a dose of 10 mg DBTC and 15 mg DPTC/kg/day for five consecutive days, they cleared the parasites from the peripheral blood of the infecte...

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Bibliographic Details
Main Authors: Shuaibu M.N., Ameh D.A., Bonire J.J., Adaudi A.O., Ibrahim S., Nok A.J.
Format: Article
Language:English
Published: EDP Sciences 2000-03-01
Series:Parasite
Subjects:
organotin
Trypanosoma brucei brucei
trypanocidal
Online Access:http://dx.doi.org/10.1051/parasite/2000071043

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