A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab

Pulmonary vein thrombosis (PVT) is a challenging diagnosis and has been described in association with or as a complication of pulmonary tumors, lung surgeries, atrial myxoma, and after radiofrequency catheter ablation for atrial fibrillation. There are not many reported cases of PVT associated with...

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Main Authors: Sandhya Narukonda MD, Nagadarshini Ramagiri Vinod MD, Medha Joshi MD
Format: Article
Language:English
Published: SAGE Publishing 2017-08-01
Series:Journal of Investigative Medicine High Impact Case Reports
Online Access:https://doi.org/10.1177/2324709617724176
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author Sandhya Narukonda MD
Nagadarshini Ramagiri Vinod MD
Medha Joshi MD
author_facet Sandhya Narukonda MD
Nagadarshini Ramagiri Vinod MD
Medha Joshi MD
author_sort Sandhya Narukonda MD
collection DOAJ
description Pulmonary vein thrombosis (PVT) is a challenging diagnosis and has been described in association with or as a complication of pulmonary tumors, lung surgeries, atrial myxoma, and after radiofrequency catheter ablation for atrial fibrillation. There are not many reported cases of PVT associated with medication use. We present a case of a 53-year-old male with a history of severe persistent asthma on omalizumab, who presented with shortness of breath and was found to have PVT on computed tomography scan of the chest. The hypercoagulable workup was normal, and the patient did not have a history of malignancy or pulmonary surgeries. Currently, available data suggest an association between omalizumab use and increased risk of arterial thrombotic events. However, on a literature search, we could not find any reported cases of PVT with omalizumab treatment.
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spelling doaj.art-4b8fe58057144a1cb7b4994dc90b5cbf2022-12-22T01:37:56ZengSAGE PublishingJournal of Investigative Medicine High Impact Case Reports2324-70962017-08-01510.1177/2324709617724176A Case of Pulmonary Vein Thrombosis Associated With Treatment of OmalizumabSandhya Narukonda MD0Nagadarshini Ramagiri Vinod MD1Medha Joshi MD2Conemaugh Memorial Medical Center, Johnstown, PA, USAConemaugh Memorial Medical Center, Johnstown, PA, USAConemaugh Memorial Medical Center, Johnstown, PA, USAPulmonary vein thrombosis (PVT) is a challenging diagnosis and has been described in association with or as a complication of pulmonary tumors, lung surgeries, atrial myxoma, and after radiofrequency catheter ablation for atrial fibrillation. There are not many reported cases of PVT associated with medication use. We present a case of a 53-year-old male with a history of severe persistent asthma on omalizumab, who presented with shortness of breath and was found to have PVT on computed tomography scan of the chest. The hypercoagulable workup was normal, and the patient did not have a history of malignancy or pulmonary surgeries. Currently, available data suggest an association between omalizumab use and increased risk of arterial thrombotic events. However, on a literature search, we could not find any reported cases of PVT with omalizumab treatment.https://doi.org/10.1177/2324709617724176
spellingShingle Sandhya Narukonda MD
Nagadarshini Ramagiri Vinod MD
Medha Joshi MD
A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab
Journal of Investigative Medicine High Impact Case Reports
title A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab
title_full A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab
title_fullStr A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab
title_full_unstemmed A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab
title_short A Case of Pulmonary Vein Thrombosis Associated With Treatment of Omalizumab
title_sort case of pulmonary vein thrombosis associated with treatment of omalizumab
url https://doi.org/10.1177/2324709617724176
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