Molecular Behavior of HMGB1 in the Cochlea Following Noise Exposure and in vitro

Molecular Behavior of HMGB1 in the Cochlea Following Noise Exposure and in vitro

Noise-induced hearing loss (NIHL) is characterized by cellular damage to the inner ear, which is exacerbated by inflammation. High-mobility group box 1 (HMGB1), a representative damage-associated molecular pattern (DAMP), acts as a mediator of inflammation or an intercellular messenger according to...

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Bibliographic Details
Main Authors: Lili Xiao, Yan Sun, Chengqi Liu, Zhong Zheng, Ying Shen, Liang Xia, Guang Yang, Yanmei Feng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
noise
hearing loss
cochlea
high-mobility group box 1
spatiotemporal distribution
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.642946/full

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