Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients
Abstract Background Esophageal varices (EV) is the most common apprehensive complication of portal hypertension in patients with cirrhotic liver. Guidelines recommend Upper gastro-intestinal endoscopic screening for EV in patients with newly diagnosed chronic cirrhosis (Imperiale et al. in Hepatolog...
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| Format: | Article |
| Language: | English |
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SpringerOpen
2022-01-01
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| Series: | The Egyptian Journal of Radiology and Nuclear Medicine |
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| Online Access: | https://doi.org/10.1186/s43055-021-00681-0 |
| _version_ | 1818941739798364160 |
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| author | Mohamed Alaa ELdin Nouh Mohamed Kamel Abd-Elmageed Amany Abas Mohamed Amer Moamena Said ELhamouly |
| author_facet | Mohamed Alaa ELdin Nouh Mohamed Kamel Abd-Elmageed Amany Abas Mohamed Amer Moamena Said ELhamouly |
| author_sort | Mohamed Alaa ELdin Nouh |
| collection | DOAJ |
| description | Abstract Background Esophageal varices (EV) is the most common apprehensive complication of portal hypertension in patients with cirrhotic liver. Guidelines recommend Upper gastro-intestinal endoscopic screening for EV in patients with newly diagnosed chronic cirrhosis (Imperiale et al. in Hepatology 45(4):870–878, 2007). Yet, it is invasive, time consuming and costly. To avoid unnecessary endoscopy, some studies have suggested Doppler ultrasound examination as simple, and noninvasive tool in prediction and assessment of severity of EV (Agha et al. in Dig Dis Sci 54(3):654–660, 2009). Our study was to assess the role of different Doppler indices of portal vein, hepatic and splenic arteries as a noninvasive tool for prediction of esophageal varices in cirrhotic patients. Results This prospective case control study was conducted on 100 cirrhotic liver patients and 100 of healthy volunteers as control group. Patients were subjected to clinical examination, upper gastrointestinal tract endoscopy, abdominal ultrasonography with duplex Doppler evaluation of different portal Doppler hemodynamic indices were done for each patient. The results revealed that portal vein diameter, hepatic artery pulsatility index, portal hypertensive index, portal vein flow velocity, portal congestion index have high sensitivity for prediction of EV. However, Splenic artery resistance index, hepatic artery resistance index HARI, liver vascular index and platelet count/spleen diameter have less sensitivity for prediction of EV. Conclusion Measuring the portal hemodynamic indices can help physicians as noninvasive predictors of EV in cirrhotic patients to restrict the need for unnecessary endoscopic screening especially when endoscopic facilities are limited. |
| first_indexed | 2024-12-20T07:00:20Z |
| format | Article |
| id | doaj.art-4b926cadfe934d6f9527a0c08b9f2402 |
| institution | Directory Open Access Journal |
| issn | 2090-4762 |
| language | English |
| last_indexed | 2024-12-20T07:00:20Z |
| publishDate | 2022-01-01 |
| publisher | SpringerOpen |
| record_format | Article |
| series | The Egyptian Journal of Radiology and Nuclear Medicine |
| spelling | doaj.art-4b926cadfe934d6f9527a0c08b9f24022022-12-21T19:49:14ZengSpringerOpenThe Egyptian Journal of Radiology and Nuclear Medicine2090-47622022-01-0153111110.1186/s43055-021-00681-0Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patientsMohamed Alaa ELdin Nouh0Mohamed Kamel Abd-Elmageed1Amany Abas Mohamed Amer2Moamena Said ELhamouly3Department of Tropical Medicine, Menoufia University Faculty of MedicineDepartment of Radiodiagnosis and Interventional Radiology, Menoufia University Faculty of MedicineDepartment of Tropical Medicine, Menoufia University Faculty of MedicineDepartment of Tropical Medicine, Menoufia University Faculty of MedicineAbstract Background Esophageal varices (EV) is the most common apprehensive complication of portal hypertension in patients with cirrhotic liver. Guidelines recommend Upper gastro-intestinal endoscopic screening for EV in patients with newly diagnosed chronic cirrhosis (Imperiale et al. in Hepatology 45(4):870–878, 2007). Yet, it is invasive, time consuming and costly. To avoid unnecessary endoscopy, some studies have suggested Doppler ultrasound examination as simple, and noninvasive tool in prediction and assessment of severity of EV (Agha et al. in Dig Dis Sci 54(3):654–660, 2009). Our study was to assess the role of different Doppler indices of portal vein, hepatic and splenic arteries as a noninvasive tool for prediction of esophageal varices in cirrhotic patients. Results This prospective case control study was conducted on 100 cirrhotic liver patients and 100 of healthy volunteers as control group. Patients were subjected to clinical examination, upper gastrointestinal tract endoscopy, abdominal ultrasonography with duplex Doppler evaluation of different portal Doppler hemodynamic indices were done for each patient. The results revealed that portal vein diameter, hepatic artery pulsatility index, portal hypertensive index, portal vein flow velocity, portal congestion index have high sensitivity for prediction of EV. However, Splenic artery resistance index, hepatic artery resistance index HARI, liver vascular index and platelet count/spleen diameter have less sensitivity for prediction of EV. Conclusion Measuring the portal hemodynamic indices can help physicians as noninvasive predictors of EV in cirrhotic patients to restrict the need for unnecessary endoscopic screening especially when endoscopic facilities are limited.https://doi.org/10.1186/s43055-021-00681-0Oesophageal varicesPortal hypertensionDoppler ultrasound |
| spellingShingle | Mohamed Alaa ELdin Nouh Mohamed Kamel Abd-Elmageed Amany Abas Mohamed Amer Moamena Said ELhamouly Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients The Egyptian Journal of Radiology and Nuclear Medicine Oesophageal varices Portal hypertension Doppler ultrasound |
| title | Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients |
| title_full | Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients |
| title_fullStr | Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients |
| title_full_unstemmed | Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients |
| title_short | Role of portal color Doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients |
| title_sort | role of portal color doppler ultrasonography as noninvasive predictive tool for esophageal varices in cirrhotic patients |
| topic | Oesophageal varices Portal hypertension Doppler ultrasound |
| url | https://doi.org/10.1186/s43055-021-00681-0 |
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