Thymol alleviates AGEs-induced podocyte injury by a pleiotropic effect via NF-κB-mediated by RhoA/ROCK signalling pathway

Thymol alleviates AGEs-induced podocyte injury by a pleiotropic effect via NF-κB-mediated by RhoA/ROCK signalling pathway

Advanced glycation end products (AGE) are those of the most powerful pathogenic factors that related to diabetic complications. In our study, we investigated the beneficial effects of thymol on AGE induced cell injury and apoptosis in human podocytes (HPCs) and attempted to clarify its mechanisms. O...

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Bibliographic Details
Main Authors: Qinglian Wang, Zhenwei Shen, Guanghui Qi, Yanfang Zhao, Hongge Zhang, Rong Wang
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Cell Adhesion & Migration
Subjects:
thymol
advanced glycation end products (age)
human podocytes
rhoa/rock pathway
nuclear factor-kappa b (nf-κb)
Online Access:http://dx.doi.org/10.1080/19336918.2020.1721172

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