ADAMTS-15 Has a Tumor Suppressor Role in Prostate Cancer

ADAMTS-15 Has a Tumor Suppressor Role in Prostate Cancer

Extracellular matrix remodeling has emerged as an important factor in many cancers. Proteoglycans, including versican (VCAN), are regulated via cleavage by the proteolytic actions of A Disintegrin-like And Metalloproteinase domain with Thrombospondin-1 motif (ADAMTS) family members. Alterations in t...

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Bibliographic Details
Main Authors: Marley J. Binder, Scott McCoombe, Elizabeth D. Williams, Daniel R. McCulloch, Alister C. Ward
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Biomolecules
Subjects:
ADAMTS
ECM
prostate cancer
tumor suppressor
VCAN
versikine
Online Access:https://www.mdpi.com/2218-273X/10/5/682

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