Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres
Abstract Background Cigarette smoking in people with cancer is associated with negative treatment-related outcomes including increased treatment toxicity and complications, medication side effects, decreased performance status and morbidity. Evidence-based smoking cessation care is not routinely pro...
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| Format: | Article |
| Language: | English |
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BMC
2021-03-01
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| Series: | Implementation Science |
| Subjects: | |
| Online Access: | https://doi.org/10.1186/s13012-021-01092-5 |
| _version_ | 1819141511303921664 |
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| author | Christine L. Paul Graham Warren Shalini Vinod Bettina Meiser Emily Stone Daniel Barker Kate White James McLennan Fiona Day Kristen McCarter Melissa McEnallay Jordan Tait Karen Canfell Marianne Weber Catherine Segan |
| author_facet | Christine L. Paul Graham Warren Shalini Vinod Bettina Meiser Emily Stone Daniel Barker Kate White James McLennan Fiona Day Kristen McCarter Melissa McEnallay Jordan Tait Karen Canfell Marianne Weber Catherine Segan |
| author_sort | Christine L. Paul |
| collection | DOAJ |
| description | Abstract Background Cigarette smoking in people with cancer is associated with negative treatment-related outcomes including increased treatment toxicity and complications, medication side effects, decreased performance status and morbidity. Evidence-based smoking cessation care is not routinely provided to patients with cancer. The purpose of this study is to determine the effectiveness of a smoking cessation implementation intervention on abstinence from smoking in people diagnosed with cancer. Methods A stepped wedge cluster randomised design will be used. All sites begin in the control condition providing treatment as usual. In a randomly generated order, sites will move to the intervention condition. Based on the Theoretical Domains Framework, implementation of Care to Quit will include (i) building the capability and motivation of a critical mass of key clinical staff and identifying champions; and (ii) identifying and implementing cessation care models/pathways. Two thousand one hundred sixty patients with cancer (diagnosed in the prior six months), aged 18+, who report recent combustible tobacco use (past 90 days or in the 30 days prior to cancer diagnosis) and are accessing anti-cancer therapy, will be recruited at nine sites. Assessments will be conducted at baseline and 7-month follow-up. The primary outcome will be 6-month abstinence from smoking. Secondary outcomes include biochemical verification of abstinence from smoking, duration of quit attempts, tobacco consumption, nicotine dependence, provision and receipt of smoking cessation care, mental health and quality of life and cost effectiveness of the intervention. Discussion This study will implement best practice smoking cessation care in cancer centres and has the potential for wide dissemination. Trial registration The trial is registered with ANZCTR (www.anzctr.org.au): ACTRN ( ACTRN12621000154808 ) prior to the accrual of the first participant and will be updated regularly as per registry guidelines. |
| first_indexed | 2024-12-22T11:55:37Z |
| format | Article |
| id | doaj.art-4b9d54e7459d4fe995cf70249f7821e2 |
| institution | Directory Open Access Journal |
| issn | 1748-5908 |
| language | English |
| last_indexed | 2024-12-22T11:55:37Z |
| publishDate | 2021-03-01 |
| publisher | BMC |
| record_format | Article |
| series | Implementation Science |
| spelling | doaj.art-4b9d54e7459d4fe995cf70249f7821e22022-12-21T18:26:48ZengBMCImplementation Science1748-59082021-03-0116111410.1186/s13012-021-01092-5Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centresChristine L. Paul0Graham Warren1Shalini Vinod2Bettina Meiser3Emily Stone4Daniel Barker5Kate White6James McLennan7Fiona Day8Kristen McCarter9Melissa McEnallay10Jordan Tait11Karen Canfell12Marianne Weber13Catherine Segan14University of Newcastle Priority Research Centre for Cancer Research, Innovation and TranslationDepartment of Radiation Oncology, Department of Cell and Molecular Pharmacology, Medical University of South CarolinaCancer Therapy Centre, Liverpool HospitalPrince of Wales Clinical School, University of New South WalesSt Vincent’s Hospital Sydney, Kinghorn Cancer Centre, University of NSWUniversity of Newcastle School of Medicine and Public HealthFaculty of Medicine and Health, University of Sydney, CNRU Sydney Local Health DistrictSt Vincent’s Hospital SydneyUniversity of Newcastle School of Medicine and Public HealthUniversity of Newcastle Priority Research Centre for Cancer Research, Innovation and TranslationUniversity of Newcastle Priority Research Centre for Cancer Research, Innovation and TranslationUniversity of Newcastle School of Medicine and Public HealthCancer Research Division, Cancer Council NSWCancer Research Division, Cancer Council NSWCancer Council VictoriaAbstract Background Cigarette smoking in people with cancer is associated with negative treatment-related outcomes including increased treatment toxicity and complications, medication side effects, decreased performance status and morbidity. Evidence-based smoking cessation care is not routinely provided to patients with cancer. The purpose of this study is to determine the effectiveness of a smoking cessation implementation intervention on abstinence from smoking in people diagnosed with cancer. Methods A stepped wedge cluster randomised design will be used. All sites begin in the control condition providing treatment as usual. In a randomly generated order, sites will move to the intervention condition. Based on the Theoretical Domains Framework, implementation of Care to Quit will include (i) building the capability and motivation of a critical mass of key clinical staff and identifying champions; and (ii) identifying and implementing cessation care models/pathways. Two thousand one hundred sixty patients with cancer (diagnosed in the prior six months), aged 18+, who report recent combustible tobacco use (past 90 days or in the 30 days prior to cancer diagnosis) and are accessing anti-cancer therapy, will be recruited at nine sites. Assessments will be conducted at baseline and 7-month follow-up. The primary outcome will be 6-month abstinence from smoking. Secondary outcomes include biochemical verification of abstinence from smoking, duration of quit attempts, tobacco consumption, nicotine dependence, provision and receipt of smoking cessation care, mental health and quality of life and cost effectiveness of the intervention. Discussion This study will implement best practice smoking cessation care in cancer centres and has the potential for wide dissemination. Trial registration The trial is registered with ANZCTR (www.anzctr.org.au): ACTRN ( ACTRN12621000154808 ) prior to the accrual of the first participant and will be updated regularly as per registry guidelines.https://doi.org/10.1186/s13012-021-01092-5SmokingSmoking cessationCancerImplementationQuitline |
| spellingShingle | Christine L. Paul Graham Warren Shalini Vinod Bettina Meiser Emily Stone Daniel Barker Kate White James McLennan Fiona Day Kristen McCarter Melissa McEnallay Jordan Tait Karen Canfell Marianne Weber Catherine Segan Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres Implementation Science Smoking Smoking cessation Cancer Implementation Quitline |
| title | Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres |
| title_full | Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres |
| title_fullStr | Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres |
| title_full_unstemmed | Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres |
| title_short | Care to Quit: a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres |
| title_sort | care to quit a stepped wedge cluster randomised controlled trial to implement best practice smoking cessation care in cancer centres |
| topic | Smoking Smoking cessation Cancer Implementation Quitline |
| url | https://doi.org/10.1186/s13012-021-01092-5 |
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