CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge

CaMKIIα Expressing Neurons to Report Activity-Related Endogenous Hypoxia upon Motor-Cognitive Challenge

We previously introduced the brain erythropoietin (EPO) circle as a model to explain the adaptive ‘brain hardware upgrade’ and enhanced performance. In this fundamental circle, brain cells, challenged by motor-cognitive tasks, experience functional hypoxia, triggering the expression of EPO among oth...

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Bibliographic Details
Main Authors: Umer Javed Butt, Imam Hassouna, Laura Fernandez Garcia-Agudo, Agnes A. Steixner-Kumar, Constanze Depp, Nadine Barnkothe, Matthias R. Zillmann, Anja Ronnenberg, Viktoria Bonet, Sandra Goebbels, Klaus-Armin Nave, Hannelore Ehrenreich
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
physiological hypoxia
complex running wheel
hippocampus
scRNA-seq
light-sheet microscopy
Hif-1α
Online Access:https://www.mdpi.com/1422-0067/22/6/3164

Internet

https://www.mdpi.com/1422-0067/22/6/3164

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