4-BENZOYLPYRIDINE OXIME DERIVATIVE (GIZH-298) VERSUS VALPROIC ACID: THE ANTICONVULSANT POTENTIAL EFFECT IN A MODEL OF EPILEPSY IN RATS WITH COBALT-INDUCED LESIONS

4-BENZOYLPYRIDINE OXIME DERIVATIVE (GIZH-298) VERSUS VALPROIC ACID: THE ANTICONVULSANT POTENTIAL EFFECT IN A MODEL OF EPILEPSY IN RATS WITH COBALT-INDUCED LESIONS

Objective of the research is to evaluate the anticonvulsant effect of the new original compound GIZH-298 (4-benzoylpyridine oxime derivative) versus valproic acid (VPA) in a model of epilepsy in rats with cobalt-induced lesions.Materials and methods. Modeling of epileptic status was performed using...

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Bibliographic Details
Main Authors:	I. O. Gaydukov, S. A. Litvinova, T. A. Voronina, L. N. Nerobkova, L. A. Zhmurenko, G. V. Mokrov, G. G. Avakyan, I. S. Kutepova
Format:	Article
Language:	Russian
Published:	IRBIS LLC 2017-08-01
Series:	Эпилепсия и пароксизмальные состояния
Subjects:	gizh-298 4-benzoylpyridine oxime derivative epilepsy valproic acid status epilepticus seizures eeg homocysteine thiolactone. cobalt-induced epilepsy rats.
Online Access:	https://www.epilepsia.su/jour/article/view/346

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