Autopsy findings of miliary tuberculosis in a renal transplant recipient

Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive tr...

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Main Authors: Khushdeep Shergill, Divya Shelly, Manoj G, Ritu Ranjan Kumar
Format: Article
Language:English
Published: University of São Paulo 2017-09-01
Series:Autopsy and Case Reports
Subjects:
Online Access:http://www.revistas.usp.br/autopsy/article/view/139571
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author Khushdeep Shergill
Divya Shelly
Manoj G
Ritu Ranjan Kumar
author_facet Khushdeep Shergill
Divya Shelly
Manoj G
Ritu Ranjan Kumar
author_sort Khushdeep Shergill
collection DOAJ
description Miliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive treatment at the earliest possible time. However, a considerable number of cases are missed ante-mortem. We discuss the case of a 32-year-old immunocompromised, non-HIV patient with an ante-mortem diagnosis of pulmonary TB. However, multiple organ involvement by Mycobacterium tuberculosis was demonstrated on autopsy. This case highlights the role of autopsy as a research and learning tool, and prudential clinico-pathologic correlation, which will improve clinical outcomes in the future
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spelling doaj.art-4ba4959087fd42a491ea01fe31e165de2022-12-21T17:59:13ZengUniversity of São PauloAutopsy and Case Reports2236-19602017-09-017310.4322/acr.2017.026Autopsy findings of miliary tuberculosis in a renal transplant recipientKhushdeep Shergill0Divya Shelly1Manoj G2Ritu Ranjan Kumar3Maharashtra University of Health Sciences, Armed Forces Medical College, Department of PathologyMaharashtra University of Health Sciences, Armed Forces Medical College, Department of PathologyMaharashtra University of Health Sciences, Armed Forces Medical College, Department of PathologyMaharashtra University of Health Sciences, Armed Forces Medical College, Department of PathologyMiliary tuberculosis is a lethal form of disseminated tuberculosis (TB), deriving its name from the millet-seed-sized granulomas in multiple organs. As TB still remains a leading cause of morbidity and mortality in India, its disseminated forms need to be diagnosed early to ensure more aggressive treatment at the earliest possible time. However, a considerable number of cases are missed ante-mortem. We discuss the case of a 32-year-old immunocompromised, non-HIV patient with an ante-mortem diagnosis of pulmonary TB. However, multiple organ involvement by Mycobacterium tuberculosis was demonstrated on autopsy. This case highlights the role of autopsy as a research and learning tool, and prudential clinico-pathologic correlation, which will improve clinical outcomes in the futurehttp://www.revistas.usp.br/autopsy/article/view/139571Miliary TuberculosisRenal TransplantAutopsy
spellingShingle Khushdeep Shergill
Divya Shelly
Manoj G
Ritu Ranjan Kumar
Autopsy findings of miliary tuberculosis in a renal transplant recipient
Autopsy and Case Reports
Miliary Tuberculosis
Renal Transplant
Autopsy
title Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_full Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_fullStr Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_full_unstemmed Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_short Autopsy findings of miliary tuberculosis in a renal transplant recipient
title_sort autopsy findings of miliary tuberculosis in a renal transplant recipient
topic Miliary Tuberculosis
Renal Transplant
Autopsy
url http://www.revistas.usp.br/autopsy/article/view/139571
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AT divyashelly autopsyfindingsofmiliarytuberculosisinarenaltransplantrecipient
AT manojg autopsyfindingsofmiliarytuberculosisinarenaltransplantrecipient
AT rituranjankumar autopsyfindingsofmiliarytuberculosisinarenaltransplantrecipient